Publications by authors named "A Tyler Putnam"

With the increasing age of the population in the USA, fall prevention events to target older patients are imperative. The American Association for the Surgery of Trauma hosted a fall prevention event at the host city of the 2023 Annual Meeting. We review the planning and implementation of this "Stop the Falls" event, in hopes that other institutions may benefit and sustainably effectuate fall prevention events for an increasingly geriatric population.

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The development of perfusable and multiscale vascular networks remains one of the largest challenges in tissue engineering. As such, there is a need for the creation of customizable and facile methods to produce robustly vascularized constructs. In this study, secondarily crosslinkable (clickable) poly(ethylene glycol)-norbornene (PEGNB) microbeads were produced and evaluated for their ability to sequentially support suspension bioprinting and microvascular self-assembly towards the aim of engineering hierarchical vasculature.

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Article Synopsis
  • Telangiectases and arteriovenous malformations (AVMs) are key features of Hereditary Hemorrhagic Telangiectasia (HHT), linked to genetic mutations in specific HHT-related genes.
  • Researchers analyzed DNA from various tissue samples from individuals with HHT to understand the genetic mechanisms behind AVM formation and found somatic second-hit mutations contributing to these lesions.
  • This study is the first to demonstrate that both nasal telangiectasias and solid organ AVMs in HHT are associated with low-level somatic biallelic second-hit mutations, highlighting the complexity of HHT's genetic landscape.*
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Background: Geriatric trauma patients are an increasing population of the United States (US), sustaining a high incidence of falls, and suffer greater morbidity and mortality to their younger counterparts. Significant variation and challenges exist to optimize outcomes for this cohort, while being mindful of available resources. This manuscript provides concise summary of locoregional and national practices, including relevant updates in the triage of geriatric trauma in an effort to synthesize the results and provide guidance for further investigation.

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Developmental venous anomalies (DVAs) are clinically benign, low-flow vascular malformations that classically hemorrhage only when associated with a cerebral cavernous malformation. It is very rare for an isolated DVA to hemorrhage. Resection of the DVA is generally contraindicated because of the high risk of venous infarct.

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