Design, development and performance of a Fe-Mn-Si-Cu alloy for bioabsorbable medical implants.

Bioabsorbable metallic alloys constitute a very challenging and innovative field, mainly aimed to develop the next generation of temporary medical implants. Degradation data, biological and tests are of major importance in particular for complex alloys, in which the individual element additions could enhance material performance and add functionalities. In this study, a novel Fe-Mn-Si-Cu alloy was carefully designed for vascular and blood-contact applications, and its microstructure, mechanical behavior, degradation behavior and biological performances were investigated accordingly.

Biological Characterization of Ti6Al4V Additively Manufactured Surfaces: Comparison Between Ultrashort Laser Texturing and Conventional Post-Processing.

Among Additive Manufacturing (AM) technologies, Laser Powder Bed Fusion (LPBF) has made a great contribution to optimizing the production of customized implant materials. However, the design of the ideal surface topography, capable of exerting the best biological effect without drawbacks, is still a subject of study. The aim of the present study is to topographically and biologically characterize AM-produced Ti6Al4V ELI (Extra Low Interstitial) samples by comparing different surface finishing.

Impact of Surface Finishing on Ti6Al4V Voronoi Additively Manufactured Structures: Morphology, Dimensional Deviation, and Mechanical Behavior.

Additively manufactured medical devices require proper surface finishing before their use to remove partially adhered particles and provide adequate surface roughness. The literature widely investigates regular lattice structures-mainly scaffolds with small pores to enhance osseointegration; however, only a few studies have addressed the impact of surface finishing on the dimensional deviation and the global and local mechanical responses of lattice samples. Therefore, the current research investigates the impact of biomedical surface finishing (i.

Effect of trabecular architectures on the mechanical response in osteoporotic and healthy human bone.

Research at the mesoscale bone trabeculae arrangement yields intriguing results that, due to their clinical resolution, can be applied in clinical field, contributing significantly to the diagnosis of bone-related diseases. While the literature offers quantitative morphometric parameters for a thorough characterization of the mesoscale bone network, there is a gap in understanding relationships among them, particularly in the context of various bone pathologies. This research aims to bridge these gaps by offering a quantitative evaluation of the interplay among morphometric parameters and mechanical response at mesoscale in osteoporotic and non-osteoporotic bones.

In Vitro Assessment of the Neuro-Compatibility of Fe-20Mn as a Potential Bioresorbable Material for Craniofacial Surgery.

Spring-assisted surgery is a popular option for the treatment of non-syndromic craniosynostosis. The main drawback of this procedure is the need for a second surgery for spring removal, which could be avoided if a distractor material could be metabolised over time. Iron-Manganese alloys (FeMn) have a good trade-off between degradation rate and strength; however, their biocompatibility is still debated.