Publications by authors named "A Tufano"
Article Synopsis
- This study aimed to analyze how common surgically induced chronic kidney disease (CKD-S) is in patients with upper tract urothelial carcinoma (UTUC) after they undergo radical nephroureterectomy (RNU), focusing on survival outcomes.* -
- Researchers looked at data from 1,862 patients and found that 34.7% developed CKD-S3a and 39.6% developed CKD-S3b after surgery, with older age, lower preoperative kidney function, and certain chemotherapy treatments linked to higher risks of developing CKD-S3b.* -
- The study revealed that while CKD-S3b patients had worse overall survival rates (59% over 5 years), CK
Background: Oxidative stress has emerged as a key contributor to numerous NCDs (non-communicable diseases), including cardiovascular diseases, cancer, and diabetes. This study aims to explore the potential of targeted interventions to mitigate oxidative stress as part of a primary prevention strategy.
Methods: The study included 32 healthy participants (11 men, 21 women) aged 45-65 who completed both the initial and follow-up assessments of the Healthy Days Initiative, a community-based wellness program organized by the non-profit Associazione O.
Article Synopsis
- The study investigates the effects of neoadjuvant and adjuvant chemotherapy on survival rates in patients with Upper tract urothelial carcinoma undergoing Nephroureterectomy, using data from a multicenter registry.
- A total of 1,994 patients were analyzed, revealing that neoadjuvant chemotherapy notably improved cancer-specific and overall survival, especially in patients with advanced tumors or positive nodes.
- The results suggest a significant survival benefit from neoadjuvant chemotherapy, indicating a need for further research to explore its impact in this patient population.