Publications by authors named "A Tudo"

Article Synopsis
  • Pufferfish, known for being highly toxic due to neurotoxins like tetrodotoxins and paralytic shellfish toxins, poses a serious risk to human health and has caused many poisoning incidents.
  • A study analyzed tissue extracts from two pufferfish species collected from the Spanish Mediterranean, revealing no toxicity in Sphoeroides pachygaster but significant toxicity in the liver of Lagocephalus lagocephalus specimens.
  • High-performance liquid chromatography analysis confirmed the presence of paralytic shellfish toxins, particularly saxitoxin and decarbamoylsaxitoxin, in L. lagocephalus, highlighting a food safety concern due to the potential risks associated with consuming this toxic fish in the region. *
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Tetrodotoxin (TTX) is a marine toxin responsible for many intoxications around the world. Its presence in some pufferfish species and, as recently reported, in shellfish, poses a serious health concern. Although TTX is not routinely monitored, there is a need for fast, sensitive, reliable, and simple methods for its detection and quantification.

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Ciguatera Poisoning (CP) is caused by consumption of fish or invertebrates contaminated with ciguatoxins (CTXs). Presently CP is a public concern in some temperate regions, such as Macaronesia (North-Eastern Atlantic Ocean). Toxicity analysis was performed to characterize the fish species that can accumulate CTXs and improve understanding of the ciguatera risk in this area.

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Article Synopsis
  • Dinoflagellates from certain genera are known to produce toxic compounds like ciguatoxins and maitotoxins, with many species still poorly studied in areas like the western Mediterranean Sea.
  • A strain from the Balearic Islands was previously analyzed and found to produce compounds such as 44-methyl gambierone and gambieric acids C and D but lacked the typical MTX1 found in Pacific strains.
  • This study identified a new MTX analogue, MTX5, in the Mediterranean strain, demonstrating that it produces different toxins compared to Pacific strains and highlighting the challenges in identifying ciguatoxin precursors in this region.
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Gambierdiscus and Fukuyoa are genera of toxic dinoflagellates which were mainly considered as endemic to marine intertropical areas, and that are well known as producers of ciguatoxins (CTXs) and maitotoxins (MTXs). Ciguatera poisoning (CP) is a human poisoning occurring after the consumption of fish or more rarely, shellfish containing CTXs. The presence of these microalgae in a coastal area is an indication of potential risk of CP.

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