Forecasting Pediatric Trauma Volumes: Insights From a Retrospective Study Using Machine Learning.

Introduction: Rising pediatric firearm-related fatalities in the United States strain Trauma Centers. Predicting trauma volume could improve resource management and preparedness, particularly if daily forecasts are achievable. The aim of the study is to evaluate various machine learning models' accuracy on monthly, weekly, and daily data.

Association of psychosocial factors at work with fertility and menstrual disorders: A systematic review.

Objectives: This systematic review aimed to assess the association between psychosocial factors in the workplace and menstrual abnormalities or fertility, focusing on literature implementing a prospective cohort design.

Methods: We searched MEDLINE, EMBASE, PsycINFO, PsycARTICLES, and Japan Medical Abstracts Society electronic databases for studies published from inception to February 26, 2020, and updated the search in PubMed on May 29, 2024. Inclusion criteria were (P) adult female workers (over 18 years old), (E) presence of adverse psychosocial factors at work, (C) absence of adverse psychosocial factors at work, and (O) any menstrual cycle disorders, menstrual-related symptoms, or fertility issues.

Vocational identity in decision-making for terminating/continuation of pregnancy following non-invasive prenatal testing and hypothetical diagnosis among Japanese university students.

The use of prenatal testing in Japan is expected to increase. However, there are ethical concerns regarding pregnancy termination upon the detection of fetal chromosomal abnormalities, such as Down syndrome. Furthermore, factors associated with decision-making following a positive result of Down syndrome after prenatal screening remain unclear.

Effectiveness of a Smartphone-Based Stress Management Program for Depression in Hospital Nurses During COVID-19 in Vietnam and Thailand: 2-Arm Parallel-Group Randomized Controlled Trial.

Background: During the COVID-19 pandemic, health care professionals experienced high levels of depression. However, extant research has not highlighted effective internet-based psychological interventions to improve the mental health in this population during the pandemic. It remains unclear whether self-guided, internet-based cognitive behavioral therapy (iCBT) programs are effective in improving the mental health of health care workers during the COVID-19 pandemic.

Studies of the Synthesis and the Structure-activity Relationship of 3-Methylflavones.

Background/aim: Flavonoids represent a privileged scaffold for medicinal chemists because of versatile synthetic transformation into a large variety of functionalized derivatives and are known to exhibit a variety of biological activities and their potential as anticancer agents is being investigated. As part of our continuing investigation of flavonoid derivatives as potential anticancer substances, a series of 3-methylflavones were synthesized, and their antiproliferative activity was evaluated in leukemic HL60 cells.

Materials And Methods: 3-Methylflavones were directly synthesized from the 2-propionylphenyl benzoate esters prepared from combination of 2'-hydroxypropiophenone with appropriate benzoic acid derivatives by the modified conditions of Yamaguchi esterification.