Publications by authors named "A Tsiakou"
Article Synopsis
- Changes in pigmented melanocytic lesions have been observed after laser or IPL hair removal treatments, with studies showing significant clinical and dermoscopic alterations.
- In clinical evaluations, 20-100% of individuals experienced changes, while dermoscopic alterations were reported in 48%-93% of nevi, with common findings including bleaching and irregular pigmented areas.
- Diagnostic approaches for these atypical lesions may involve complex techniques like confocal microscopy and digital dermoscopy, highlighting the need for caution during procedures to prevent potential melanoma risks.
Background and Objectives: Triple-negative breast cancer (TNBC) is a highly heterogeneous subtype that is associated with unresponsiveness to therapy and hence with high mortality rates. In this study we aimed to investigate the prognostic role of the rs822336 G>C and rs822337 T>A polymorphisms of the PD-L1 (Programmed Death-Ligand 1) in TNBC patients. Materials and methods: Formalin-fixed paraffin-embedded tissues from 114 TNBC patients and blood samples from 124 healthy donors were genotyped, and subsequently extensive statistical analysis was performed in order to investigate the clinical value of these polymorphism in TNBC.
View Article and Find Full Text PDFThe purpose of this study is to evaluate the role of MET T1010I and MET rs40239 as potential risk factor and/or prognostic markers in patients with triple-negative breast cancer (TNBC). 114 samples of DNA from paraffin-embedded breast normal tissues of patients with TNBC and 124 samples of healthy controls were collected and analyzed for MET T1010I and MET rs40239 polymorphisms. MET T1010I CT genotype was associated with increased risk of TNBC in both univariate and multivariate analysis.
View Article and Find Full Text PDFObjectives: The aim of this was the assessment of the prognostic role of the rs4938723 C > T polymorphism of the miR-34 in triple negative breast cancer patients.
Methods: Therefore formalin fixed paraffin embedded tissue samples from 114 triple negative breast cancer patients and blood samples from 124 healthy donors were genotyped and subsequently extensive statistical analysis was performed in order to investigate the clinical value of this polymorphism in triple negative breast cancer.
Results: Our statistical analysis disclosed that the majority of patients harboring ductal breast carcinoma (69.