Single-dock Robotic Bilateral Transversus Abdominis Release: Technique Description and Preliminary Outcomes.

Background: Posterior component separation with transversus abdominis release (TAR) is a valuable adjunct to address incisional hernia defects. Currently, bilateral docking is a standard technique for robotic TAR. The aim of this study is to describe our technique for extended totally extraperitoneal (eTEP) repair with bilateral TAR through a bottom single-dock robotic approach for hernias at the level of the umbilicus or higher.

Macrophage LRRK2 hyperactivity impairs autophagy and induces Paneth cell dysfunction.

polymorphisms (G2019S/N2081D) that increase susceptibility to Parkinson's disease and Crohn's disease (CD) lead to LRRK2 kinase hyperactivity and suppress autophagy. This connection suggests that LRRK2 kinase inhibition, a therapeutic strategy being explored for Parkinson's disease, may also benefit patients with CD. Paneth cell homeostasis is tightly regulated by autophagy, and their dysfunction is a precursor to gut inflammation in CD.

Exploring Veterinary Students' Perceptions of Teamwork and Learning from an Interprofessional Community-based Experience.

The COVID-19 pandemic provided insight into the gaps provided by health care systems that could benefit from collaborative practice across the nexus of the animal and human health professions. The platform of Interprofessional Education (IPE), recognized as a pedagogical platform for delivering the principles of One Health, embodies the benefits of collaboration to address critical emerging public health issues, including the emergence of vector-borne zoonoses, antimicrobial resistance, food security and defense and the impacts of climatic change. A phenomenological methodology, which is used to understand individuals lived experience, elicited veterinary students' perceptions of the benefits of interprofessional learning.

Elective complex ventral hernia repair in contaminated fields: A propensity score-matched analysis of long-term quality of life and outcomes between different prostheses.

Background: Randomized studies have endorsed nonabsorbable prosthetics for contaminated ventral hernia surgery, yet the broader applicability and impact on patient-reported outcomes are still questioned. Here, we evaluated the long-term outcomes of elective contaminated ventral hernia repairs (based on Centers of Disease Control and Prevention [CDC] wound classification) using real-world data from a multicenter US cohort, focusing on quality of life and postoperative pain.

Methods: The Abdominal Core Health Quality Collaborative database was queried for patients undergoing elective contaminated (CDC class II-IV) ventral hernia repair (2013-2023).