Individual neuronal subtypes control initial myelin sheath growth and stabilization.

Background: In the developing central nervous system, pre-myelinating oligodendrocytes sample candidate nerve axons by extending and retracting process extensions. Some contacts stabilize, leading to the initiation of axon wrapping, nascent myelin sheath formation, concentric wrapping and sheath elongation, and sheath stabilization or pruning by oligodendrocytes. Although axonal signals influence the overall process of myelination, the precise oligodendrocyte behaviors that require signaling from axons are not completely understood.

[Sitting on administrative boards].

Because of the strategic role they play and the important contribution they make to health and social services establishments, nurses are being asked more frequently to participate as members of administrative boards. The author illustrates, in a legislative context, the public-centred approach at the heart of health and social service reform in Quebec. The author outlines a specific role for these administrative boards in establishing a new health and social service system.