Coagulopathy due to celiac disease presenting as intramuscular hemorrhage.

Introduction: Celiac sprue most commonly presents with steatorrhea, abdominal pain, and weight loss. Celiac disease is now becoming more recognized for its atypical presentations. Anemia, osteoporosis, and childhood failure to thrive have been widely discussed.

The role of lysosomal alterations in the damage to the pancreas and liver in acute experimental pancreatitis in dogs.

The role of lysosomal hydrolases in the pathogenesis of acute pancreatitis and secondary liver injury, as an important aspect of multisystem organ failure, remains unclear. The purpose of this study was to assess the lysosomal fragility in both organs in acute experimental pancreatitis (AEP) of graded severity in dogs. In 7 dogs, the moderate (M) and in 13 dogs severe (S) variant of bile--trypsin AEP--was induced; 6 dogs were in control group (C).

Severity of Helicobacter-induced gastric injury correlates with gastric juice ammonia.

We postulated that ammonia produced by Helicobacter pylori may contribute to gastric mucosal injury. This hypothesis was evaluated in Helicobacter-positive patients with chronic renal failure in whom a high urea concentration might amplify this phenomenon. Gastric urea and ammonia were measured, and the severity of gastritis was evaluated by counting mononuclear and polymorphonuclear cells.

Human exocrine pancreatic secretion changes associated with age.

A retrospective study of data from 2352 secretin tests has been studied. Age-related changes in the structure and function of the gastrointestinal tract have been the subject of many publications. There is a consensus that basal and stimulated gastric secretion declines with age.