Motivation: Long-read sequencing technologies can be employed to detect and map DNA modifications at the nucleotide resolution on a genome-wide scale. However, published software packages neglect the integration of genomic annotation and comprehensive filtering when analyzing patterns of modified bases detected using Pacific Biosciences (PacBio) or Oxford Nanopore Technologies (ONT) data. Here, we present DNA Modification Annotation (DNAModAnnot), a R package designed for the global analysis of DNA modification patterns using adapted filtering and visualization tools.
View Article and Find Full Text PDFOxygen isotope compositions of bone phosphate (δO) were measured in broiler chickens reared in 21 farms worldwide characterized by contrasted latitudes and local climates. These sedentary birds were raised during an approximately 3 to 4-month period, and local precipitation was the ultimate source of their drinking water. This sampling strategy allowed the relationship to be determined between the bone phosphate δO values (from 9.
View Article and Find Full Text PDFThe oxygen isotope compositions of bones (n = 11) and teeth (n = 20) from 12 Sudanese individuals buried on Sai Island (Nubia) were analysed to investigate the registration of the evolution of the Nile environment from 3700 to 500 years BP and the potential effects of ontogeny on the oxygen isotope ratios. The isotopic compositions were converted into the composition of drinking water, ultimately originating from the Nile. δO values decrease during ontogeny; this is mainly related to breastfeeding and physiology.
View Article and Find Full Text PDFPhys Rev E Stat Nonlin Soft Matter Phys
January 2002
Formal neurons implementing wavelets have been shown to build nets that are able to approximate any multidimensional task. In this paper, we use a finite number of formal neurons implementing elementary tasks such as "sombrero" responses or even simpler "window" responses, with adjustable widths. We show this to provide a reasonably efficient, practical and robust, multifrequency analysis of tasks.
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