Publications by authors named "A Touzeau"

Motivation: Long-read sequencing technologies can be employed to detect and map DNA modifications at the nucleotide resolution on a genome-wide scale. However, published software packages neglect the integration of genomic annotation and comprehensive filtering when analyzing patterns of modified bases detected using Pacific Biosciences (PacBio) or Oxford Nanopore Technologies (ONT) data. Here, we present DNA Modification Annotation (DNAModAnnot), a R package designed for the global analysis of DNA modification patterns using adapted filtering and visualization tools.

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Article Synopsis
  • In Paramecium tetraurelia, a significant portion of the germline genome is removed from the somatic genome after sexual events, involving small RNA-directed processes, but the specifics of how this recognition occurs in chromatin are still unclear.
  • The study identifies a homolog of the histone chaperone Spt16 in P. tetraurelia, revealing its crucial role in eliminating germline-limited sequences and facilitating the survival of offspring, while also regulating the localization of the PiggyMac endonuclease necessary for DNA elimination.
  • Spt16-1 does not influence the early steps of the scanRNA-directed pathway but is vital for the interactions between chromatin and the excision machinery, providing
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Oxygen isotope compositions of bone phosphate (δO) were measured in broiler chickens reared in 21 farms worldwide characterized by contrasted latitudes and local climates. These sedentary birds were raised during an approximately 3 to 4-month period, and local precipitation was the ultimate source of their drinking water. This sampling strategy allowed the relationship to be determined between the bone phosphate δO values (from 9.

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The oxygen isotope compositions of bones (n = 11) and teeth (n = 20) from 12 Sudanese individuals buried on Sai Island (Nubia) were analysed to investigate the registration of the evolution of the Nile environment from 3700 to 500 years BP and the potential effects of ontogeny on the oxygen isotope ratios. The isotopic compositions were converted into the composition of drinking water, ultimately originating from the Nile. δO values decrease during ontogeny; this is mainly related to breastfeeding and physiology.

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Formal neurons implementing wavelets have been shown to build nets that are able to approximate any multidimensional task. In this paper, we use a finite number of formal neurons implementing elementary tasks such as "sombrero" responses or even simpler "window" responses, with adjustable widths. We show this to provide a reasonably efficient, practical and robust, multifrequency analysis of tasks.

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