Publications by authors named "A Toskas"
Varioliform gastritis (VG) is a rare chronic gastritis characterized by mucosal protrusions with central depressions, typically found in the stomach. This paper discusses the first reported case of VG extending into the duodenum, involving a 68-year-old immunocompromised patient with a complex medical history, including prostate cancer and multiple comorbidities. The diagnosis was complicated by the presence of , which was treated successfully with eradication therapy consisting of amoxicillin and clarithromycin along with omeprazole.
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- The study investigated the expression levels of IL-19 and IL-24 in patients with inflammatory bowel disease (IBD) compared to healthy controls, and how these levels change before and after biologic treatment.
- Researchers measured IL-19 and IL-24 in intestinal tissue samples from 121 IBD patients and found elevated levels in IBD patients, with IL-19 being linked to disease activity after treatment.
- The findings suggest that both IL-19 and IL-24 play significant roles in the inflammation associated with IBD and could potentially serve as biomarkers for tracking disease activity and treatment response.
Unlabelled: Ulcerative colitis (UC) is an autoimmune disease associated with both intestinal and extraintestinal manifestations. The latter may include heart complications, such as myopericarditis leading to life-threatening arrythmias. Nowadays, UC is commonly treated with biologic medications and infliximab is the first line therapy in an outpatient setting, while it is also used as rescue therapy in acute severe UC.
View Article and Find Full Text PDFInterleukins are potential therapeutic targets that can alter the prognosis and progression of inflammatory bowel disease (IBD). The roles of IL-6, IL-10, IL-17, and IL-23 have been extensively studied, setting the stage for the development of novel treatments for patients with IBD. Other cytokines have been less extensively studied.
View Article and Find Full Text PDFThe direct and practical oxidative anomeric -glycosylation of glycosyl iodides with an array of alcohols as glycosyl acceptors is presented. Using phenyliodine(III) diacetate (PIDA) as the promoter of the reaction, at ambient temperature, an enviromentally benign and operationally simple protocol has been developed providing access stereoselectively to 1,2--glycosides.
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