Publications by authors named "A Torne"
Objective: Endocervical curettage (ECC) is the gold standard for predicting the persistence of high-grade squamous intraepithelial lesions (HSIL) after cervical conization. However, ECC has a high rate of unsatisfactory samples and may be uncomfortable for women. Endocervical sampling with brush (ECB) has been proposed as an alternative to ECC, which, in addition to the cytological evaluation, allows performing HPV testing using the same sample.
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- Hypoxic reactivation of Kaposi's sarcoma-associated herpesvirus (KSHV) occurs when the virus shifts from a dormant state to active replication under low oxygen conditions, unlike healthy cells that typically halt reproduction.
- Cancerous cells, similar to KSHV, adapt their physiology to continue dividing in hypoxic environments by altering their metabolism and other cellular processes.
- The study highlights how KSHV uses specific viral antigens to manipulate host cell functions, allowing the virus to successfully replicate and persist even when oxygen levels are low.
Objective: Prehabilitation, defined as the preparatory intervention to increase patient preparedness in the lead-up to surgery, has shown a decrease in post-operative complications in various types of surgery. However, there is limited evidence in advanced ovarian cancer surgery. This study aimed to evaluate the benefits of multimodal prehabilitation in advanced ovarian cancer patients in terms of improving physical functioning, body composition, and psychological well-being during the pre-operative period.
View Article and Find Full Text PDFTo assess the long-term oncological safety of laparoscopic fertility-sparing surgery (FSS) in borderline ovarian tumors and the impact of laparoscopic surgical factors on recurrences. Primary outcomes were the recurrence rate and time to recurrence after laparoscopic FSS. Secondary outcomes were to evaluate the recurrence rate after a second laparoscopic surgery and to assess factors associated with the risk of relapse.
View Article and Find Full Text PDFBackground: This study evaluated the clinical outcomes of applying a 68 Gy EQD2 dose constraint to the most exposed 2 cm area of the vagina in post-operative endometrial cancer patients treated with vaginal-cuff brachytherapy after external beam irradiation and the impact of vaginal dilator use on late vaginal complications.
Material And Methods: We analyzed 131 patients treated with vaginal-cuff brachytherapy after external beam irradiation. Group-1 (65 patients) received one fraction of 7 Gy, and Group-2 (66 patients) received one fraction of between 5.