Publications by authors named "A Topal"
Study Design: Prospective biochemical study of comparison of A Disintegrin and Metalloproteinase with Thrombospondin motifs-4 (ADAMTS-4) and A Disintegrin and Metalloproteinase with Thrombospondin motifs 5 (ADAMTS5) levels in preoperative and postoperative venous blood, as well as in disc tissue obtained during surgery, in patients undergoing surgery for intervertebral disc disease, with enzyme levels in venous blood from a control group.
Objective: To compare the levels of ADAMTS-4 and ADAMTS-5 between patients with degenerative intervertebral discs and a healthy control group, aiming to identify biomarkers associated with intervertebral disc degeneration.
Literature: Although numerous studies have investigated the relationship between ADAMTS-4 and ADAMTS-5 enzymes and degeneration in experimental rat models and human tissues, no study has correlated their serum levels with intervertebral disc degeneration.
Plant diseases threaten agricultural sustainability by reducing crop yields. Rapid and accurate disease identification is crucial for effective management. Recent advancements in artificial intelligence (AI) have facilitated the development of automated systems for disease detection.
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- The study investigates if the Charlson Comorbidity Index (CCI) can predict the occurrence of pseudoarthrosis in patients after short-segment lumbar decompression and fusion for degenerative spine disorders.
- Data was collected from patients treated between 2013 and 2023, analyzing their comorbidities, smoking status, and anthropometric measures using the Subcutaneous Fat Index (SFI).
- The findings suggest that higher CCI scores are linked to increased rates of pseudoarthrosis post-surgery, with a notable cut-off score of 2.5 indicating a higher risk in patients.