Paragangliomas (PGLs) are rare neuroendocrine extra-adrenal tumors that could be secreting mass. The symptoms are the typical triad of paroxysmal headache, hypertension and sweating, but could also be accompanied by symptoms involving multiple organs. Surgery is the gold standard treatment for both PGLs and pheochromocytomas (PHEOs).
View Article and Find Full Text PDFEvery year in Italy, about 60,000 new cases of nodular thyroid pathology are diagnosed, of which almost 30% are cytologically indeterminate (TIR3A/3B). The risk of malignancy reported in the literature on thyroid nodules ranges from 5% to 15% for TIR3A and from 15% to 30% for TIR3B. It is suspected that these percentages are higher in practice.
View Article and Find Full Text PDFSustainability is here to stay. As businesses migrate away from fossil fuels and toward renewable sources, chemistry will play a crucial role in bringing the economy to a point of net-zero emissions. In fact, chemistry has always been at the forefront of developing new or enhanced materials to fulfill societal demands, resulting in goods with appropriate physical or chemical qualities.
View Article and Find Full Text PDFThe RXN for Chemistry project, initiated by IBM Research Europe - Zurich in 2017, aimed to develop a series of digital assets using machine learning techniques to promote the use of data-driven methodologies in synthetic organic chemistry. This research adopts an innovative concept by treating chemical reaction data as language records, treating the prediction of a synthetic organic chemistry reaction as a translation task between precursor and product languages. Over the years, the IBM Research team has successfully developed language models for various applications including forward reaction prediction, retrosynthesis, reaction classification, atom-mapping, procedure extraction from text, inference of experimental protocols and its use in programming commercial automation hardware to implement an autonomous chemical laboratory.
View Article and Find Full Text PDFThe world is on the verge of a new industrial revolution, and language models are poised to play a pivotal role in this transformative era. Their ability to offer intelligent insights and forecasts has made them a valuable asset for businesses seeking a competitive advantage. The chemical industry, in particular, can benefit significantly from harnessing their power.
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