Publications by authors named "A Tokushige"

Background: In posterior-stabilized (PS) total knee arthroplasty (TKA), joint extension gap decreases after placement of a femoral trial component which causes imbalance between the extension and flexion gaps. Previous studies have demonstrated that capsular release around the intercondylar notch can enlarge the extension gap; however, its impact on the flexion gap is unknown. This study assessed the effect of capsular release around the intercondylar notch on both extension and flexion gaps.

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  • - The study examined the clinical characteristics and risk factors associated with severe COVID-19 cases caused by the XBB variant in Okinawa, Japan, during mid-2023.
  • - Out of 367 hospitalized patients, 18.5% were classified as severe, with older age and underlying health conditions linked to a higher mortality rate (13.2% in severe cases vs. 3.0% in mild cases).
  • - Notably, diabetes mellitus increased the risk for severe COVID-19, while receiving the bivalent omicron booster significantly reduced the severity of the disease.
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Malnutrition and inflammation are common problems of adverse outcomes in various diseases as atherosclerosis. Recently, the concept of malnutrition-inflammation-atherosclerosis (MIA) syndrome is known to a crucial prognostic factor in patients with end-stage renal disease. We investigated the prognostic impact of the co-presence of MIA factors in patients with lower-extremity artery disease (LEAD) after endovascular therapy (EVT).

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  • Calcified nodules (CNs) in coronary arteries are linked to worse health outcomes in patients with stable coronary artery disease, affecting survival rates and increasing the likelihood of major cardiovascular and cerebrovascular events.
  • A study of 619 patients showed that those with CNs had significantly lower survival rates and higher incidences of major adverse events compared to those without CNs.
  • Factors like chronic kidney disease and low serum cholinesterase levels were found to contribute to the formation of CNs, suggesting that monitoring these could be important for patient prognosis after procedures like percutaneous coronary intervention.
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  • Nonalcoholic fatty liver diseases (NAFLD) and nonalcoholic steatohepatitis (NASH) can lead to hepatocellular carcinoma (HCC), prompting a study of risk stratification methods using histological features and noninvasive markers in patients with liver biopsy-confirmed NAFLD or NASH.
  • The study included 1389 patients and compared the predictive ability of histological factors and noninvasive models such as the aMAP score, FIB-4 index, and ALBI score, revealing that the aMAP score had the highest predictive power for HCC.
  • The aMAP score and FIB-4 index were found to be superior to histological features for
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