Publications by authors named "A Tognolini"

Article Synopsis
  • Patients undergoing elective pelvic exenteration surgery are at risk of getting inadequate concentrations of the antibiotics piperacillin and tazobactam during surgery.
  • This study aimed to analyze how these antibiotics are processed in the body (pharmacokinetics) and to find better dosing recommendations to ensure effective levels during surgery.
  • Results showed that a lower continuous infusion dosage of piperacillin/tazobactam is effective in maintaining proper antibiotic levels, but patients with higher weights and kidney function might need higher doses to avoid suboptimal exposure.
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Occupationally acquired COVID-19 is a hazard for healthcare workers (HCWs). In four hospitals of the Metro North Hospitals and Health Service in Queensland, Australia, we invited HCWs to report the nature of any anaesthesia interactions with COVID-19-positive and COVID-19-suspect patients. This was to assist workforce planning in future pandemics.

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Article Synopsis
  • This study investigates how different concentrations of propofol affect the protein binding and concentration of lidocaine in human plasma used during general anesthesia.! -
  • The research involved adding specific concentrations of propofol and lidocaine to drug-free human plasma and analyzing the results using advanced chromatography techniques.! -
  • Findings showed that propofol does not significantly change the binding of lidocaine, maintaining a consistent level of protein binding similar to previous studies.!
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Objective: In patients with obesity, it was determined what proportion had an arm slant angle (SA) < 83° and which measure best predicted arm conicity. Patient experience with noninvasive blood pressure measurement was evaluated.

Methods: Arm SA was calculated from arm measurements.

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To assess the correlation between breast arterial calcifications (BAC) on digital mammography and the extent of coronary artery disease (CAD) diagnosed with dual source coronary computed tomography angiography (CTA) in a population of women both symptomatic and asymptomatic for coronary artery disease. 100 consecutive women (aged 34 - 86 years) who underwent both coronary CTA and digital mammography were included in the study. Health records were reviewed to determine the presence of cardiovascular risk factors such as hypertension, hyperlipidemia, diabetes mellitus, and smoking.

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