Publications by authors named "A Togawa"
We herein report a patient with Lynch-like syndrome in whom a brain tumor (glioblastoma) developed after repeated resection of colorectal cancer. The patient had a significant family history of cancer. Immunohistochemical expression of mismatch repair proteins was decreased in both brain and colon tumors, but no pathogenic variant of the related genes was detected.
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- Vancomycin regimens aim for an AUC/MIC ratio of 400-600 µg·h/mL, but early treatment for severe infections may depend on the first 24-hour AUC/MIC measurements.
- This study analyzed MRSA bacteremia cases to see how the first 24-hour AUC/MIC impacted treatment outcomes, using a cutoff of 300 µg·h/mL to categorize patients.
- Results showed no significant difference in treatment efficacy or 30-day survival between groups, but those with an AUC/MIC < 300 had a longer time to clinical and bacteriological improvement, suggesting that while early AUC/MIC levels do not change success rates, they may influence recovery times.
Background: Little is known whether sublingual immunotherapy using Japanese cedar pollen extract (cedar SLIT) is effective for not only Japanese cedar pollinosis but also Japanese cypress pollinosis. We investigated the prevalence rate of Japanese cypress pollinosis, efficacy of cedar SLIT on cypress pollinosis and patients' wish to receive cypress SLIT.
Methods: We investigated a multi-center (31 institutions), cross-sectional survey using a self-administrated questionnaire with four questions for patients received cedar SLIT aged from 5 to 69 years old.
Objectives: To report an isolate of Mycobacterium intracellulare subsp. chimaera with multiple mutations in 16S ribosomal RNA (rRNA) gene, resulting in the false-negative reaction to the transcription-reverse transcription concerted (TRC) method for Mycobacterium avium-intracellulare complex.
Methods: We used TRC, polymerase chain reaction (PCR), and Matrix-assisted laser desorption/ionization Time-of-Flight/Mass Spectrometry (MALDI-TOF/MS) methods to identify a clinical isolate in 2021.