Typologies of activity-related behaviours during adolescence and their transitions: a longitudinal analysis of the ELSPAC cohort.

Objectives: The objective of this study was to identify typologies of activity-related behaviours during adolescence and to explore transitions between the identified typologies. Additionally, we aimed to identify demographic indicators associated with the transitions and typology membership.

Design: Prospective cohort study.

Understanding factors influencing the use of specialized outdoor fitness equipment among older adults in Australia.

This study assessed the use of newly installed outdoor fitness equipment (OFE) designed for older adults in two urban parks in Melbourne, Australia, and explored barriers and facilitators to its use among older adults. Direct observations were conducted using System for Observing Play and Recreation in Communities (SOPARC) to assess OFE usage by older adults (≥60 years) at two time points: T1 (November 2021) and T2 (October 2022). Additionally, 140 older adults (60-86 years, 59.

Influence of park visitation on physical activity, well-being and social connectedness among Australians during COVID-19.

This cross-sectional study examined associations of park visitation with physical activity (PA), well-being, and social connectedness among 1089 participants during the coronavirus disease 2019 pandemic. In August 2020, adolescents and adults in Australia self-reported demographics, usual park visitation, frequency and duration of park visits, PA, well-being and social connectedness. Multilevel linear regression models examined associations of park visitation with well-being and social connectedness.

Thioredoxin-interacting protein (TXNIP) is a substrate of the NEDD4-like E3 ubiquitin-protein ligase WWP1 in cellular redox state regulation of acute myeloid leukemia cells.

The HECT-type E3 ubiquitin WWP1 (also known as NEDD4-like E3 ubiquitin-protein ligase WWP1) acts as an oncogenic factor in acute myeloid leukemia (AML) cells. WWP1 overexpression in AML confers a proliferative advantage to leukemic blasts (abnormal immature white blood cells) and counteracts apoptotic cell death and differentiation. In an effort to elucidate the molecular basis of WWP1 oncogenic activities, we identified WWP1 as a previously unknown negative regulator of thioredoxin-interacting protein (TXNIP)-mediated reactive oxygen species (ROS) production in AML cells.

Get BusActive!: Protocol of a single-blinded randomised controlled trial incentivising public transport use for physical activity gain among young people and adults.

Background: Population level physical activity generally does not meet recommended targets. Compared with private motor vehicle users, public transport users tend to be more physically active and financial incentives may encourage more public transport use, but these relationships are under-investigated. This paper describes the protocol of a randomised controlled trial that aimed to determine the effect of financially incentivising public transport use on physical activity in a regional Australian setting.