Background: Breast lesions of uncertain malignant potential, also known as B3 lesions, represent a heterogeneous group of tumors with variable malignancy risk. Surgical excision should be considered depending on clinical, radiological and histological features, family history and following informed consent. The aim of the present paper is to evaluate the positive predictive value (PPV) of diagnosis of malignancy in surgically excised B3 lesions in order to identify possible predictive upgrade criteria.
View Article and Find Full Text PDFAdenoid cystic carcinoma (ACC) of the breast is a very rare neoplasm. It presents a triple-negative phenotype in most cases, but its prognosis is generally considered to be better than other breast cancers with the same immunohistochemical pattern. Due to its controversial features, no data are available in the literature regarding a consensus approach for ACC treatment, especially for subtypes with worse prognosis like solid basaloid ACC.
View Article and Find Full Text PDFPneumomediastinum indicates the presence of air in the mediastinal space. It may be classified in three categories, based on the main causes of air dissection into the mediastinal structures: spontaneous pneumomediastinum (pnm), the most frequently encountered, post traumatic pnm and pnm secondary to non-traumatic rupture of an abdominal hollow viscus. This paper reports the experience of a major regional emergency surgery division in the management of pnm during a five years period.
View Article and Find Full Text PDFGastro-intestinal tuberculosis (TB) continues to give rise to diagnostic and therapeutic challenges. Its increasing incidence and multiple and non-specificity of symptoms and signs require special attention to establish a prompt diagnosis and not to delay treatment. The authors describe on case of colonic TB presenting with multiple episodes of subocclusion suggesting a stenosing neoplasm of the caecum.
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