Publications by authors named "A Thissen"
Toxicology is undergoing a digital revolution, with mobile apps, sensors, artificial intelligence (AI), and machine learning enabling better record-keeping, data analysis, and risk assessment. Additionally, computational toxicology and digital risk assessment have led to more accurate predictions of chemical hazards, reducing the burden of laboratory studies. Blockchain technology is emerging as a promising approach to increase transparency, particularly in the management and processing of genomic data related with food safety.
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- Researchers are investigating how SARS-CoV-2 infects lung cells by studying its protein interactions, particularly between the viral spike protein's receptor-binding domain (RBD) and the human ACE2 receptor.
- The study used computational methods like binding affinity calculations and molecular dynamics simulations to find that SARS-CoV-2 binds more strongly to ACE2 than its predecessor, SARS-CoV, and identified important water molecules at the interaction site that stabilize this binding.
- Experimental validation confirmed these findings, and the research suggests that understanding these molecular interactions could lead to new treatments and vaccines against the virus.
Seeds are vulnerable to physical and biological stresses during the germination process. Seed priming strategies can alleviate such stresses. Seed priming is a technique of treating and drying seeds prior to germination in order to accelerate the metabolic process of germination.
View Article and Find Full Text PDFVersailles Project on Advanced Materials and Standards interlaboratory study on intensity calibration for x-ray photoelectron spectroscopy instruments using low-density polyethylene.
J Vac Sci Technol A
December 2020
Article Synopsis
- The study explores using low-density polyethylene (LDPE) as an alternative calibration material for x-ray photoelectron spectrometers, instead of traditional materials like gold and silver.
- Researchers developed improved LDPE reference spectra, which led to a modest absolute offset of about 3.0% and systematic deviations averaging ±6.5% when compared to gold calibration methods.
- The study also highlights the challenges of using LDPE, including surface roughness and issues with low count rates, and provides an updated LDPE calibration protocol to enhance accuracy and consistency in the field.