Spatial-economic scenarios to increase resilience to urban flooding.

Due to accelerating climate change and the need for new development to accommodate population growth, adaptation of urban drainage systems has become a pressing issue in cities. Questions arise whether decentralised urban drainage systems are a better alternative to centralised systems, and whether Nature Based Solutions' (NBS) multifunctionality also brings economic benefits. This research aims to develop spatio-economic scenarios to support cities in increasing their resilience to urban flooding with NBS.

Monitoring Over Time of Pathological Complete Response to Neoadjuvant Chemotherapy in Breast Cancer Patients Through an Ensemble Vision Transformers-Based Model.

Background: Morphological and vascular characteristics of breast cancer can change during neoadjuvant chemotherapy (NAC). Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI)-acquired pre- and mid-treatment quantitatively capture information about tumor heterogeneity as potential earlier indicators of pathological complete response (pCR) to NAC in breast cancer.

Aims: This study aimed to develop an ensemble deep learning-based model, exploiting a Vision Transformer (ViT) architecture, which merges features automatically extracted from five segmented slices of both pre- and mid-treatment exams containing the maximum tumor area, to predict and monitor pCR to NAC.

Malleable and Static Risk Factors Associated with Boys' Patterns of Interpersonal Violence: A Latent Class Analysis.

Despite an increased risk of committing and experiencing violence among adolescent boys, little is known about either how different types of violence co-occur within individuals or their association with different risk factors. This study used a person-centered approach to (1) identify patterns in boys' perpetration and victimization across a range of 7 types of interpersonal violence (bullying, electronic aggression, sexual harassment/aggression; and psychological/ physical/sexual dating violence); and (2) examine the association of these patterns with 12 risk factors at the individual, relational, and community level to inform future prevention efforts. We used latent class analysis to identify patterns of violence among a diverse sample of 239 adolescent boys from 12 schools in 4 regions of the United States.

Treatment Sequencing and Independent Outcomes of First- and Second-Line Chemotherapy in a Retrospective Series of Patients with Biliary Tract Cancer.

Biliary tract cancers (BTCs) are aggressive neoplasms with limited therapeutic options. The amount of prospective evidence is poor, and limited data are available on the impact of treatment sequencing on survival. Here we report a real-world experience of patients with advanced BTC treated with at least three lines of therapy.