Publications by authors named "A Thacker"

Article Synopsis
  • People with early Alzheimer's disease (AD) are starting to use anti-amyloid monoclonal antibodies (mAbs) for treatment, but their views on risks and benefits are not well understood.
  • * A study involving semi-structured interviews with 22 participants revealed that they gather information from various sources like advocacy groups, the internet, and healthcare providers to make treatment decisions.
  • * Key themes identified in the study included: the desire for better understanding of the treatment, the hope for improved quality of life, and how personal and family factors shape their willingness to accept treatment despite its risks.*
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Key Points: A large eGFR discordance (., cystatin C–based eGFR >30% lower than creatinine-based eGFR) is common in older adults and increased with age. A large eGFR discordance was associated with increased risk of falls, hospitalization, and death, independent of kidney function.

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An estimated 694,550 United States service members were actively deployed to the Persian Gulf from 1990-1991. Many veterans who were deployed developed Persian Gulf War Syndrome along with chronic gastrointestinal symptoms after returning from the Persian Gulf. Our objective in this study was to determine the phenotypic expression of gastrointestinal symptom complexes in previously healthy veterans who had been stationed in the Persian Gulf.

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Background: Approximately 7.5 million older adults are homebound, who have difficulty and/or need assistance to leave their homes. In this growing population, the prevalence of people living with dementia (PLWD) is approximately 50%.

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Article Synopsis
  • The study evaluated a patient-friendly Workbook designed to help seriously ill patients and their caregivers engage in important conversations about their care.
  • Twenty-nine participants provided feedback through surveys and in-depth interviews, highlighting the Workbook's safety, acceptability, and ease of use, with ratings indicating generally positive responses.
  • The findings suggest that the Workbook is most effective when introduced by a trusted individual, emphasizing the importance of context and rapport in discussions about serious illness.
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