The development and calibration of a measurement system designed for assessing the performance of the avalanche photodiodes (APDs) used in the Compton scattering polarimeter of the CUSP project is discussed in this work. The designed system is able to characterize the APD gain GAPD and energy resolution across a wide range of temperatures (from -20 °C to +60 °C) and bias voltages Vbias (from 260 V to 410 V). The primary goal was to experimentally determine the GAPD dependence on the and Vbias in order to establish a strategy for stabilizing GAPD by compensating for fluctuations, acting on Vbias.
View Article and Find Full Text PDFThis study tests associations between purpose in life and coping, and whether coping mediates the association between purpose and cognitive function. Longitudinal data from the Midlife Development in the United States (MIDUS) study were used to investigate associations between purpose at MIDUS I and coping at MIDUS II ( = 2386). Emotion-focused and problem-focused coping were tested as mediators between purpose and cognitive function (memory, executive function, global cognition) at MIDUS III.
View Article and Find Full Text PDFBackground: This study evaluates the electroclinical features of infantile epileptic spasms syndrome (IESS) suddenly appearing in previously normal patients, aiming to describe clinical outcomes and independent predictors.
Method: We retrospectively selected a homogeneous group of patients with IESS from two Italian centers. All patients had normal development prior to IESS onset and a follow-up period lasting at least one year.
J Alzheimers Dis
November 2024
This study examines meaning in life and four neurobiomarkers implicated in dementia risk: amyloid-β 42 to 40 ratio, phosphorylated tau-181, neurofilament light, and glial fibrillary acidic protein. Adults without dementia (= 1150; = 59.89) from the UK Biobank reported their meaning in life; neurobiomarkers were assayed twice Meaning in life was unrelated to the biomarkers at either assessment (βs range -0.
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