Treatment of Residual Periodontal Pockets Using a Hyaluronic Acid-Based Gel: A 12 Month Multicenter Randomized Triple-Blinded Clinical Trial.

The aim of the present study was to evaluate the adjunctive effect of hyaluronic acid (HA) gel in the treatment of residual periodontal pockets over a 12-month period. Periodontal patients presenting at least one residual periodontal pocket 5-9 mm of depth in the anterior area were recruited from six university-based centers. Each patient was randomly assigned to subgingival instrumentation (SI) with the local adjunctive use of HA for test treatment or adjunctive use of local placebo for control treatment at baseline and after 3 months.

Treatment of hemorrhagic periodontitis using neopredin.

Thirty hemorrhagic periodontitis adult patients completed a 90-day controlled clinical study to determine the clinical effects of the antiinflammatory preparation neopredin gel containing prednisolone, neomycin sulfate and chlorhexidine when used an adjunct to scaling and root planing. The results were evaluated using the Quigley-Hein plaque index, the Schour-Massler gingival bleeding index, the Svrakov-Pissarev gingival vital staining index, the Muleman-Son sulcus bleeding index and the percentage of bleeding on probing sites. Treatment with neopredin resulted in consistently lower values of the mean plaque index score, the gingival bleeding index score, the vital staining index score and the sulcus bleeding index score at days 14.