Publications by authors named "A Tankisi"
Article Synopsis
- The study investigates the potential development of intraspinal pressure (ISP) elevation following traumatic spinal cord injury (TSCI) in a porcine model, particularly focusing on a hypothesized subdural compartment syndrome.
- Researchers conducted a randomized, sham-controlled trial over 72 hours measuring ISP changes alongside various injury protocols to assess the impact of different contusion regimes on ISP.
- Results showed no significant difference in ISP increases between TSCI and sham animals, indicating that the observed ISP changes were likely due to the surgical procedures rather than TSCI itself.
Introduction: There is an increasing focus on the prevention of secondary injuries following traumatic spinal cord injury (TSCI), especially through improvement of spinal cord perfusion and immunological modulation. Such therapeutic strategies require translational and controlled animal models of disease progression of the acute phases of human TSCI.
Research Question: Is it possible to establish a 72-h sedated porcine model of incomplete thoracic TSCI, enabling controlled use of continuous, invasive, and non-invasive modalities during the entire sub-acute phase of TSCI?
Material And Methods: A sham-controlled trial was conducted to establish the model, and 10 animals were assigned to either sham or TSCI.
Objective: To investigate the sensitivity of muscle velocity recovery cycles (MVRCs) for detecting altered membrane properties in critically ill patients, and to compare this to conventional nerve conduction studies (NCS) and quantitative electromyography (qEMG).
Methods: Twenty-four patients with intensive care unit acquired weakness (ICUAW) and 34 healthy subjects were prospectively recruited. In addition to NCS (median, ulnar, peroneal, tibial and sural nerves) and qEMG (biceps brachii, vastus medialis and anterior tibial muscles), MVRCs with frequency ramp were recorded from anterior tibial muscle.
Object: To the authors' knowledge, repeated measurements of intracranial pressure (ICP), cerebral perfusion pressure (CPP), and the degree of dural tension during different positions on the operating table (reverse Trendelenburg position [rTp]) have not been studied in patients undergoing craniotomy.
Methods: In the present study 53 patients with supratentorial cerebral tumors who underwent craniotomy in the supine position were included. Subdural ICP, mean arterial blood pressure (MABP), CPP, and jugular bulb (JB) pressure were recorded, and the degree of dural tension was analyzed while patients were in the neutral operating position and at 5, 10, and 15 degrees rTp.