Publications by authors named "A Taly"

Diverging from conventional cell division models, plant cells undergo incomplete division to generate plasmodesmata communication bridges between daughter cells. Although fundamental for plant multicellularity, the molecular events leading to bridge stabilization, as opposed to severing, remain unknown. Using electron tomography, we mapped the transition from cell plate fenestrae to plasmodesmata.

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Article Synopsis
  • The phagocyte NADPH oxidase (NOX2) is essential for the innate immune system, producing reactive oxygen species that help destroy pathogens.
  • Researchers used circular-dichroism analyses alongside past data to assess structural models of the NADPH oxidase complex created by the AI program AlphaFold2.
  • The findings detail how specific interactions and disordered regions within proteins, particularly between p47 and cytb, play a critical role in the assembly and activation of the NADPH oxidase complex.
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Unlabelled: Diverging from conventional cell division models, plant cells undergo incomplete division to generate plasmodesmata communication bridges between daughter cells. While fundamental for plant multicellularity, the molecular events leading to bridge stabilization, as opposed to severing, remain unknown. Using electron tomography, we mapped the transition from cell plate fenestrae to plasmodesmata.

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Outer mitochondrial membrane fusion, a vital cellular process, is mediated by mitofusins. However, the underlying molecular mechanism remains elusive. We have performed extensive multiscale molecular dynamics simulations to predict a model of the transmembrane (TM) domain of the yeast mitofusin Fzo1.

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