Publications by authors named "A Talele"
Treatment pattern and outcomes of leptomeningeal carcinomatosis in India - a retrospective study.
Lancet Reg Health Southeast Asia
May 2024
Background: Leptomeningeal carcinomatosis (LMC), the metastatic spread of cancer to the leptomeninges, is a rare complication and has a dismal prognosis. Due to limited data available on LMC from India, we conducted a country-wise audit of LMC across 15 centres in India.
Methods: The current study conducted in 2020, was a retrospective, multicentric audit of adult patients (aged ≥18 years) with diagnosis of LMC and who received treatment during 2010-2020.
Article Synopsis
- Cervical cancer continues to be a serious health issue in India and other low- to middle-income countries despite global declines in rates, highlighted by a survey involving 316 respondents that assessed current challenges and prevention strategies in India.
- A significant 65.8% of participants identified the screening of mothers and vaccination of daughters as the most crucial preventative measures, with 79% reporting that screening is provided to eligible asymptomatic women.
- There is strong support (93%) for including HPV vaccination in the national immunization program, although the high cost of the vaccine is a major barrier; however, with a new affordable HPV vaccine soon to be available, there is optimism regarding improved prevention efforts against cervical cancer.
Gallbladder cancer (GBC) is one of the most frequently observed cancers in India that is usually diagnosed at an advanced stage. Although surgery remains the only curative option, the majority of GBCs are unresectable. Palliative chemotherapy with gemcitabine and cisplatin is the recommended treatment in such cases.
View Article and Find Full Text PDFThe management of breast cancer with advanced disease or metastasis is a common problem in India and other countries. A panel of 13 oncology experts deliberated on the sidelines of the 35th Indian Cooperative Oncology Network Conference held in Mumbai to formulate an expert opinion recommendation on the novel drug delivery system (NDDS) formulations in the treatment of metastatic breast cancer (MBC). The survey comprised of 39 questions related to limitations of conventional formulations and therapeutic positioning of NDDS formulations of docetaxel, paclitaxel and doxorubicin in the management of MBC.
View Article and Find Full Text PDFAleukemic Leukemia Cutis Presenting as a Sole Sign of Relapsed Paediatric Acute Lymphoblastic Leukemia.
Indian J Hematol Blood Transfus
June 2016
The author describes paediatric case of relapsed acute lymphoblastic leukaemia (ALL) presented as aleukemic leukaemia cutis (ALC). A 2 year old child was admitted in tertiary oncology centre. He suffered from pre B cell ALL with absent Philadelphia chromosome.
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