Publications by authors named "A Takkar"
Article Synopsis
- Therapeutic plasma exchange (TPE) can lead to low calcium levels due to the use of Anticoagulant Citrate Dextrose Solution A, and adding different concentrations of calcium gluconate to human serum albumin may help prevent this issue.* -
- A study comparing two groups of TPE procedures found that while intraprocedural calcium levels were similar, post-procedural ionized calcium was significantly lower in the group with less calcium, leading to more cases of symptomatic hypocalcemia and vasovagal reactions.* -
- The results suggest that using a higher concentration of calcium gluconate (18.6 mg of elemental calcium/100 ml) is safer and more effective in maintaining calcium levels during
Background: There is a limited number of studies assessing the alterations in nerve function impairment (NFI) in leprosy over an extended period of time. To the best of our knowledge, no published study has evaluated neurological state longitudinally during treatment utilizing a combination of clinical, functional (activity limitation), electrophysiological, and patient-reported quality of life (QOL) outcomes.
Methods: This prospective, observational study included leprosy patients of all spectra.
Article Synopsis
- - The study investigates the effectiveness of plasma exchange (PE) compared to intravenous immunoglobulins (IVIg) as treatments for acute attacks of neuromyelitis optica spectrum disorder (NMOSD), focusing on disability and daily living improvement.
- - Researchers enrolled 43 NMOSD patients, dividing them into two groups: one received PE and steroids, while the other received IVIg and steroids, tracking their progress using disability and daily living scores, along with antibody levels over time.
- - Results showed significant improvements in disability and daily living scores for both treatment groups, but no significant differences between them; however, PE led to a notable decrease in anti-AQP4 antibody levels, suggesting it may be a more effective
Article Synopsis
- Cerebral vasospasm (CV) is a major complication after subarachnoid hemorrhage from aneurysms, but its molecular causes are not well understood.
- Researchers used RNA sequencing to analyze genes from samples of ruptured intracranial aneurysms (IAs) to find differences between cases with and without vasospasm.
- They identified several dysregulated genes and revealed a pattern of gene expression linked to the progression of aneurysm development and vasospasm, offering new insights for future research in this area.