Diacylglycerol kinase alpha regulates post-hepatectomy liver regeneration.

Diacylglycerol kinases (DGKs) phosphorylate diacylglycerol to generate phosphatidic acid, which plays important roles in intracellular signal transduction. DGKα is reportedly associated with progression of tumors, including hepatocellular carcinomas, but its relationship with liver regeneration has not been examined. The purpose of this research is to elucidate the role of DGKα in liver regeneration.

A Novel Surgical Solution for Sciatic Hernia: Exploring the Totally Extraperitoneal Approach.

Sciatic hernia, a rare type of pelvic floor hernia, presents significant diagnostic and therapeutic challenges. We report the first totally extraperitoneal (TEP) repair of a sciatic hernia, which was performed in a 63-year-old woman who presented with vomiting and poor dietary intake. Computed tomography revealed a strangulated femoral hernia and an incidental herniation of the sigmoid colon through the right sciatic foramen.

Coccydynia Improved by Percutaneous Discectomy.

Usually, coccydynia cases are caused by herniated discs, with lower back pain and sciatica as initial symptoms. However, whether lumbar disc herniation causes coccydynia without back pain remains unclear. We report a case of lumbar disc herniation diagnosed as the underlying cause of coccydynia by discoblock.

Risk Factors and Management of Portal Vein Thrombosis after Hepatectomy: A Single-Center Experience.

Objective: This study investigated the risk factors and management of portal vein thrombosis (PVT) after hepatectomy.

Background: PVT after hepatectomy can cause liver dysfunction and portal hypertension, and may be fatal. However, it has not been sufficiently investigated.

A case of simultaneous pancreatoduodenectomy and living donor liver transplantation for biliary cancer complicated with congenital biliary dilatation.

Background: In patients with pancreaticobiliary maljunction complicated by congenital biliary dilatation, the pancreatic enzyme flows back into the bile, leading to bile duct carcinogenesis. Although the biliary tract resection and reconstruction is well documented to decrease the rate of malignancy, cancer occurrence has been reported in the residual intrahepatic or intrapancreatic bile duct, even after resection. We report a case of multiple biliary tract cancers in the liver complicated by congenital biliary dilatation, whose tumor lesions were resected en bloc without disconnecting the biliary tract by simultaneous pancreatoduodenectomy and living donor liver transplantation.