Publications by authors named "A Take"
Article Synopsis
- - The study investigates how the expression of Mac-2 binding protein (M2BP) in the liver relates to fat accumulation and changes in the liver environment in patients with metabolic dysfunction associated steatotic liver disease (MASLD).
- - Liver samples from 46 MASLD patients were analyzed for M2BP expression using immunohistochemical staining, revealing a higher M2BP staining grade in sinusoidal cells compared to hepatocytes, and a correlation between hepatocyte staining and liver inflammation.
- - Results indicate that fat accumulation triggers M2BP expression linked to liver inflammation in hepatocytes and fibrosis in sinusoidal cells, suggesting a complex role of M2BP in MASLD pathology.
Article Synopsis
- A 67-year-old Japanese woman with liver cirrhosis from primary biliary cholangitis was admitted to the hospital after losing consciousness.
- She was diagnosed with hepatic encephalopathy (HE) through imaging and symptoms assessment.
- Molecular tests showed a link between urease-positive S. salivarius found in her saliva and stool, suggesting it may contribute to increased ammonia production and subsequent HE in cirrhosis patients.
Introduction: Limited data are available on the correlation between microbial communities and metabolic dysfunction-associated fatty liver disease (MAFLD). This study aimed to evaluate the influence of MAFLD on diverse microbial communities.
Methods: We recruited 43 patients with a nonviral liver disease.
Objective: To investigate the association between body composition and prognosis in patients with advanced hepatocellular carcinoma treated with atezolizumab plus bevacizumab.
Methods: This cohort study analysed 119 patients who received atezolizumab plus bevacizumab for unresectable hepatocellular carcinoma. We investigated the association between body composition and progression-free survival and overall survival.
Aim: We performed genomic analysis to study the relative abundance of a urease-positive Streptococcus salivarius group isolated from the saliva of patients with chronic liver disease.
Methods: Male and female patients with chronic liver disease aged over 20 years were included. First, we assessed the frequency and type of the S.