Publications by authors named "A Takarada"
Article Synopsis
- - A 61-year-old woman with symptoms of pancytopenia and febrile neutropenia underwent imaging that revealed mild enlargement of her liver and spleen, along with an abdominal abscess, but no swollen lymph nodes.
- - Bone marrow tests indicated severe fibrosis and identified the presence of specific lymphocytes, leading to the diagnosis of lymphoplasmacytic lymphoma (LPL), confirmed by genetic testing showing a MYD88 mutation.
- - After receiving weekly Rituximab treatment for a month, follow-up tests showed the lymphoma cells had vanished, myelofibrosis was nearly resolved, and the MYD88 mutation was no longer detectable.
Background: Aplastic or twig-like middle cerebral artery (Ap/T-MCA) is a congenital MCA anomaly. It may present with symptoms of both hemorrhage and ischemia, similar to moyamoya disease, and hemodynamic stress may play an essential role in the development of symptoms in both clinical entities. The optimal treatment remains controversial in symptomatic patients with Ap/T-MCA.
View Article and Find Full Text PDFFatty acid synthase (Fasn) is a key component of energy metabolism that is dynamically induced by food intake. Although extensive studies have revealed a number of transcription factors involved in the fasting/refeeding transition of Fasn expression in hepatocytes, much less evidence is available for adipocytes. Using the in vivo Ad-luc analytical system, we identified the inverted CCAAT element (ICE) around -100 nucleotides in the Fasn promoter as a critical cis-element for the refeeding response in adipocytes.
View Article and Find Full Text PDFHepatic lipogenesis is nutritionally regulated (i.e., downregulated during fasting and upregulated during the postprandial state) as an adaptation to the nutritional environment.
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