Publications by authors named "A Takahata"

Epcoritamab, a bispecific T-cell engager (BiTE) antibody targeting CD3 and CD20, has shown significant efficacy in treating refractory diffuse large B-cell lymphoma (DLBCL). However, its use can lead to severe side effects, such as tumor flare. Here, we report the case of an 84-year-old male with relapsed DLBCL who developed fatal unilateral pleural effusion following Epcoritamab treatment.

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Background: Fetal skeletal dysplasia (FSD) is a group of systemic bone and cartilage disorders that develop prenatally and can be detected using fetal ultrasonography. However, it is unsuitable for skeletal analysis because it is reflected by supersonic waves in the bone cortex. Three-dimensional computed tomography (3D-CT) is a suitable alternative and has improved the differential diagnosis of FSD during pregnancy.

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Symbiotic marine invertebrates can be small, hidden or difficult to find, hampering the understanding of their distribution and ecological roles. is a polychaete inhabiting the gorgonian , where it lives in high densities within the host's coenenchyme and occupies burrows formed by host tissue near coral polyps. This study provides the first records of since its description in 1956, from colonies of Anthogorgiidae in southern Japan.

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The patient was a 38-year-old man who was admitted to our hospital with fever, vomiting and unclear speech. Blood tests showed hemolytic anemia, thrombocytopenia, and elevated creatinine, and a Coombs test was negative. ADAMTS13 activity was <1% and ADAMTS13 inhibitor was 0.

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Article Synopsis
  • Primary leptomeningeal malignant lymphoma (PLML) is a rare form of primary central nervous system lymphoma (PCNSL) with no established treatment due to its uniqueness.* -
  • A case study of a 46-year-old male with PLML showed complete remission after treatment with a combination of chemotherapy (R-MPV and intrathecal agents) and autologous stem-cell transplantation (ASCT) using a thiotepa regimen.* -
  • A literature review indicated that ASCT has been successfully used in three reported cases of PLML, suggesting it may be an effective consolidation therapy, but more research is necessary to develop standardized treatment guidelines.*
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