The Uptake of the Influenza Vaccine in Patients With Cystic Fibrosis: A Retrospective Study.

Background: Children with cystic fibrosis are more likely to become severely unwell with influenza-associated illness compared to children without chronic lung disease. The provision of accessible influenza vaccinations is essential in the prevention of infection.

Objectives: To describe the prevalence of the influenza vaccine uptake in children with cystic fibrosis from 2016 to 2020 at a single tertiary paediatric hospital site and determine if the COVID pandemic of 2020 and the introduction of telehealth encounters affected the vaccine uptake.

Perception of Socioeconomic Status: A Meta-Analysis of Manipulations.

The causal effects of one's socioeconomic status (SES) on outcomes are typically examined by experimentally manipulating SES self-perceptions based on one of three SES dimensions-absolute resource, relative resource, and general social position. We investigated the efficacy of these manipulations by systematically meta-analyzing their effects on SES self-perceptions. Based on 107 eligible samples ( = 26,203), manipulations of SES self-perceptions across the three SES dimensions were effective overall ( = 0.

Dengue and Zika virus NS4B proteins differ in topology and in determinants of ER membrane protein complex dependency.

Flaviviruses utilize the cellular endoplasmic reticulum (ER) for all aspects of their lifecycle. Genome replication and other viral activities take place in structures called replication organelles (ROs), which are invaginations induced in the ER membrane. Among the required elements for RO formation is the biogenesis of viral nonstructural proteins NS4A and NS4B.

An osteopathic assessment of lower extremity somatic dysfunctions in runners.

Context: Runners often experience acute/chronic pain due to pre-existing structural somatic dysfunction and/or acquired various overuse injuries of the lower extremity, specifically affecting the ligaments, tendons, muscles, and bones. Common structural and function dysfunctions include but are not limited to patellofemoral pain syndrome (PFPS), Achilles tendonitis, iliotibial band syndrome (ITBS), ligamentous and muscle tears, muscle sprains/strains, stress fractures, pes planus, plantar fasciitis, and shin splints.

Objectives: The purpose of this study is to assess the correlation between acute and chronic pain, overuse injuries, and observational and palpatory findings upon evaluation to establish common trends of somatic dysfunctions and determine possible etiology of the pain/injury.