Publications by authors named "A Tagoola"

Pneumonia is the leading cause of death in children globally. In low- and middle-income countries (LMICs) pneumonia diagnosis relies on accurate assessment of respiratory rate, which can be unreliable when completed by nurses with less-advanced training. To inform more accurate measurements, we investigate the repeatability of the RRate app used by nurses in Ugandan district hospitals.

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Objectives: Each year, 5.3 million children under 5 years of age die in low-resource settings, often due to delayed recognition of disease severity, inadequate treatment, or a lack of supplies. We describe the use of a comprehensive digital facility-readiness survey tool, recently developed by the Pediatric Sepsis Data CoLaboratory, which aims to identify target areas for quality improvement related to pediatric emergency and critical care.

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Article Synopsis
  • Pneumonia is a major cause of death in children under 5, particularly among those with poor nutrition, making it important to identify body composition measures that can predict survival rates in these patients.* -
  • This study analyzed 369 children aged 6-59 months with severe pneumonia in Uganda and Kenya, comparing indices of fat and muscle mass to see which was a better predictor of 6-month survival.* -
  • Results showed that while Arm-Fat-Area had a comparable predictive ability for survival as Arm-Muscle-Area and Arm-Muscle-Circumference, none of these were significantly better than the measurement of Mid-Upper Arm Circumference (MUAC).*
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Background: Severe pneumonia in African children results in poor long-term outcomes (deaths/readmissions) with undernutrition as a key risk factor. We hypothesised additional energy/protein-rich Ready-to-Use Therapeutic Foods (RUTF) would meet additional nutritional requirements and improve outcomes.

Methods: COAST-Nutrition was an open-label Phase 2 randomised controlled trial in children (aged 6 months-12 years) hospitalised with severe pneumonia (and hypoxaemia, SpO <92%) in Mbale, Soroti, Jinja, Masaka Regional Referral Hospitals, Uganda and Kilifi County Hospital, Kenya (ISRCTN10829073 (registered 6th June 2018) PACTR202106635355751 (registered 2nd June 2021)).

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