Flow virometry: recent advancements, best practices, and future frontiers.

The imperative for developing robust tools to detect, analyze, and characterize viruses has become increasingly evident as they continue to threaten human health. In this review, we focus on recent advancements in studying human viruses with flow virometry (FV), an emerging technique that has gained considerable momentum over the past 5 years. These advancements include the application of FV in viral surface phenotyping, viral protein functionality, virus sorting, vaccine development, and diagnostics.

Cold versus hot snare endoscopic mucosal resection of colorectal polyps: meta-analysis of randomized controlled trials.

Background And Aims: Interest in cold endoscopic mucosal resection (EMR) for colorectal polyps has been growing lately. We conducted a meta-analysis of RCTs to compare cold and hot EMR for colorectal polyps.

Methods: We reviewed several databases from inception to October 06, 2024.

Comparing methods to detect cellular proteins on the surface of HIV-1 virions.

The surface of HIV-1 is embedded with numerous host-derived proteins. Characterizing these proteins can enhance knowledge of virus biology and potentially identify novel therapeutic targets. As many of these proteins are present in low abundance on virion surfaces, their identification can be hindered by inherent variables in the methods employed to detect them, including their varying assay sensitivities, sample processing, quantitative capacity, and experimental reproducibility.