Isolation, characterization and anti-inflammatory activity of compounds from the .

The need to explore the abundance of natural products cannot be overemphasized particularly in the management of various disease conditions. In traditional medical practice, has been widely adopted in the management of various inflammatory disorders. The objective of this investigation was to isolate the bioactive principles from the stem-bark and root of and assess the anti-inflammatory () activity of both the crude extracts and the isolated compounds.

Telfairia occidentalis mitigates dextran sodium sulfate-induced ulcerative colitis in rats via suppression of oxidative stress, lipid peroxidation, and inflammation.

Ulcerative colitis (UC), a subcategory of inflammatory bowel diseases, affects more than 2 million people globally. This study sought to investigate the curative ability of aqueous leaf extract of Telfairia occidentalis (ATO) on dextran sodium sulfate (DSS)-mediated colitis in rats. UC was induced by 5% of DSS in drinking water, and the curative ability of ATO was assessed at 200 mg/kg by oral administration for 10 days.

Covid-19 treatment: Investigation on the phytochemical constituents of as potential Coronavirus-2 inhibitors.

The upsurge in the current cases of COVID-19 poses a major threat on human health and population all over the globe. The emergence of new infectious diseases and increase in frequency of drug resistant viruses demand effective and novel therapeutic agents. In this study, we used bioinformatics approach to investigate the possible inhibitory potentials of phytochemical constituents of towards coronavirus-2 major protease.

Toxicity assessment of sub-acute and sub-chronic oral administration and diuretic potential of aqueous extract of calyces.

Background: Food and herbal usage of (HS) is attaining improved global relevance and acceptance without recourse to its potential toxic effects. This study investigated the safety profile of acute, sub-acute, sub-chronic administrations and diuretic potential of aqueous extract of calyces (AEHSC).

Method: Acute oral toxicity, sub-acute and sub-chronic toxicity as well as diuretic studies were carried out on HS.

A systematic review on COVID-19 pandemic with special emphasis on curative potentials of Nigeria based medicinal plants.

Despite the frightening mortality rate associated with COVID-19, there is no known approved drug to effectively combat the pandemic. COVID-19 clinical manifestations include fever, fatigue, cough, shortness of breath, and other complications. At present, there is no known effective treatment or vaccine that can mitigate/inhibit SARS-CoV-2.