Prevalence of Abdominal Obesity in Children and Adolescents with Intellectual Disability in Southeastern Poland.

: The aim of the study was to determine the frequency of occurrence of a significant health problem-abdominal obesity (AO)-in children and adolescents with intellectual disability (ID) compared to children and adolescents without disabilities, examined in the period 2013-2014. : The study group included 568 students with various ID degrees ( = 265 mild; = 249 moderate; = 54 severe) (age range 7-18 years) attending care and educational facilities. The comparison group (non-ID) was randomly selected based on the principle of matching the group (age and sex) among students without ID.

Fullerenol C(OH): Antioxidant, Cytoprotective, Anti-Influenza Virus Activity, and Self-Assembly in Aqueous Solutions and Cell Culture Media.

Viral infections and many other dangerous diseases are accompanied by the development of oxidative stress, which is a consequence of an increase in the level of the reactive oxygen species (ROS). In this regard, the search for effective antioxidants remains highly relevant. We tested fullerenol C(OH) in the context of the connection between its self-assembly in aqueous solutions and cell culture media, antiradical activity, UV cytoprotective action, and antiviral activity against international reference strains of influenza virus A(H1N1)pdm09, A(H3N2), and B subtypes in vitro on the MDCK cell line.

The Effect of Maternal Diet and Lifestyle on the Risk of Childhood Obesity.

: Childhood obesity is a global health problem that affects at least 41 million children under the age of five. Increased BMI in children is associated with serious long-term health consequences, such as type 2 diabetes, cardiovascular disease, and psychological problems, including depression and low self-esteem. Although the etiology of obesity is complex, research suggests that the diet and lifestyle of pregnant women play a key role in shaping metabolic and epigenetic changes that can increase the risk of obesity in their children.

Dissecting the Kaiso binding profile in clear renal cancer cells.

Background: There has been a notable increase in interest in the transcriptional regulator Kaiso, which has been linked to the regulation of clonal hematopoiesis, myelodysplastic syndrome, and tumorigenesis. Nevertheless, there are no consistent data on the binding sites of Kaiso in vivo in the genome. Previous ChIP-seq analyses for Kaiso contradicted the accumulated data of Kaiso binding sites obtained in vitro.

Unlocking the key to HPV prevention: Exploring factors influencing HPV vaccination decisions among young people and their parents.

Objectives: Human Papillomavirus (HPV) vaccination is a recognised preventive measure against HPV-related cancers. Despite the availability of vaccines, challenges persist, including limited awareness and gender disparities in vaccination. Addressing the challenges necessitates a comprehensive approach involving knowledge advancements, understanding societal needs and cultural beliefs, and improving vaccine communication.