Publications by authors named "A T Mattfeld"
Nucleus reuniens: Modulating emotional overgeneralization in peri-adolescents with anxiety.
Cogn Affect Behav Neurosci
October 2024
Article Synopsis
- Anxiety affects millions of children in the USA, particularly between childhood and adolescence, a time of significant neural changes impacting emotions and memory.
- The study focused on how the nucleus reuniens (RE) relates to memory specificity and negative overgeneralization in anxious youth by examining brain connectivity among participants.
- Results indicated that heightened anxiety is linked to increased activation in the RE during memory tasks and altered connectivity with brain regions like the medial prefrontal cortex (mPFC), emphasizing the RE's role in anxiety and memory processes.
Toward a mechanistic understanding of the role of error monitoring and memory in social anxiety.
Cogn Affect Behav Neurosci
October 2024
Cognitive models state that social anxiety (SA) involves biased cognitive processing that impacts what is learned and remembered within social situations, leading to the maintenance of SA. Neuroscience work links SA to enhanced error monitoring, reflected in error-related neural responses arising from mediofrontal cortex (MFC). Yet, the role of error monitoring in SA remains unclear, as it is unknown whether error monitoring can drive changes in memory, biasing what is learned or remembered about social situations.
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- Negative reinforcement may link sleep quality to alcohol use, especially in individuals with depression/anxiety, as poor sleep worsens negative emotions that alcohol can temporarily ease.
- A study involving 60 underage college students aimed to explore associations between sleep, alcohol use, and negative reinforcement learning, using wearable devices and daily sleep diaries.
- Findings revealed that while sleep timing variability and negative reinforcement learning had some positive associations with alcohol use, no indirect effects were found; however, interactions with depression and anxiety suggested these factors influence the relationship.
Pigs are an important large animal model for translational clinical research but underutilized in behavioral neuroscience. This is due, in part, to a lack of rigorous neurocognitive assessments for pigs. Here, we developed a new automated T-maze for pigs that takes advantage of their natural tendency to alternate.
View Article and Find Full Text PDFLimited options exist to evaluate the development of hippocampal function in young children. Research has established that trace eyeblink conditioning (EBC) relies on a functional hippocampus. Hence, we set out to investigate whether trace EBC is linked to hippocampal structure, potentially serving as a valuable indicator of hippocampal development.
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