Publications by authors named "A T Lefor"

Article Synopsis
  • Remifentanil is an opioid anesthetic known for its fast-acting effects, and this study investigates its use at high doses (0.5 mcg/kg/min or more) in neonatal surgeries to reduce sedation-related complications.
  • The study reviewed 15 cases of neonatal abdominal surgeries conducted between January 2016 and February 2022, noting that while hypotension occurred in 13% of patients, no bradycardia or serious post-operative complications were reported.
  • Although high-dose remifentanil maintained hemodynamic stability, concerns about respiratory depression remain, highlighting the need for further research into its long-term effects on neonates.
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Segmental grafts from living donors have advantages over grafts from deceased donors when used for small intestine transplantation. However, storage time for small intestine grafts can be extremely short and optimal graft preservation conditions for short-term storage remain undetermined. Secreted factors from mesenchymal stem cells (MSCs) that allow direct activation of preserved small intestine grafts.

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Background: The outcomes after liver transplantation have greatly improved, which has resulted in greater focus on improving non-hepatic outcomes of liver transplantation. The present study aimed to evaluate thoracic spine radio density in children and adolescents after liver transplantation.

Methods: A total of 116 patients who underwent living donor liver transplantation were retrospectively analyzed.

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Background: Masks are well accepted in Japan, where they were already part of daily life even before the COVID-19 pandemic. Unlike many other countries where mask mandates were lifted as soon as the pandemic was under control, Japan was one of the last countries to ease mask-wearing guidelines. Even after the formal announcement to allow masks-off in mid-March 2023, many Japanese still voluntarily wear masks.

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Article Synopsis
  • This study investigates the incidence and risk factors of Low Anterior Resection Syndrome (LARS) in Japanese patients who underwent anus-preserving surgery for rectal tumors.
  • The research found that 22% of patients experienced major LARS, with a higher incidence (48%) among those with lower tumors.
  • It also revealed a strong correlation between the severity of LARS and decreased quality of life, particularly in patients with lower rectal tumors.
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