Publications by authors named "A T FeSSler"
Antimicrobial susceptibility testing (AST) in the veterinary sector by broth microdilution is mainly based on commercially available microtitre plates with specific panels. A critical review of commercially available microtitre panels identified AST panels that fulfil the requirements for obtaining reliable AST results by covering the necessary antimicrobial concentrations for both clinical breakpoints as well as quality control (QC) ranges for approved QC strains. However, there are AST panels in which these prerequisites are only in part fulfilled, and some AST panels that do not fulfil the aforementioned criteria at all.
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- The study aimed to establish epidemiological cut-off values for the minimum inhibitory concentrations (MICs) of 10 antimicrobial agents against the bacteria Vibrio parahaemolyticus using standardized testing methods.
- Eight laboratories conducted broth microdilution tests at two different temperatures (35°C and 28°C) to assess the effect of incubation temperature on MIC values, finding that many values were consistent across both temperatures.
- The generated data will be submitted to the Clinical and Laboratory Standards Institute to help set international standards for interpreting antimicrobial susceptibility tests for this species.
Article Synopsis
- Antimicrobial resistance (AMR) in Enterobacterales, particularly in Escherichia coli, poses serious health and economic issues for humans and animals, highlighting the "One Health" approach to understanding this problem.
- The study aimed to find extended-spectrum cephalosporin-resistant Enterobacterales in ruminants across Rwanda's provinces and to characterize the isolates.
- From 454 rectal swabs collected from cattle, goats, and sheep, 64 resistant isolates were found, predominantly E. coli, with many showing multidrug-resistance and various resistance phenotypes linked to specific genes.
Two novel plasmids harbouring the multiresistance gene cfr in porcine Staphylococcus equorum.
J Glob Antimicrob Resist
December 2024
Article Synopsis
- Scientists are worried about a bacteria called Staphylococcus equorum that can resist many medicines because it has special genes.
- They studied one specific sample of this bacteria that has two unique pieces of DNA called plasmids that help it resist medicine.
- The findings show that these plasmids also have genes that help the bacteria survive against heavy metals, making it a bigger threat to health that needs to be monitored closely.
In the present study, the presence of the Enterobacterales, Staphylococcus spp., Mammaliicoccus spp., and Enterococcus spp.
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