Publications by authors named "A T Brawanski"
Background: Accurate and repeatable measurement of high-grade glioma (HGG) enhancing (Enh.) and T2/FLAIR hyperintensity/edema (Ed.) is required for monitoring treatment response.
View Article and Find Full Text PDFPurpose: Brain metastases (BM) can present a displacing or infiltrating growth pattern, independent of the primary tumor type. Previous studies have shown that tumor cell infiltration at the macro-metastasis/brain parenchyma interface (MMPI) is correlated with poor outcome. Therefore, a pre-therapeutic, non-invasive detection tool for potential metastatic cell infiltration at the MMPI would be desirable to help identify patients who may benefit from a more aggressive local treatment strategy.
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- The study investigates the relationship between the release of CGRP in the cerebrospinal fluid and health-related quality of life after spontaneous subarachnoid hemorrhage (sSAH).
- Twenty-six patients with sSAH underwent various treatments, and daily CSF samples were analyzed for CGRP levels while patients reported their health status using standardized assessments.
- Higher CGRP levels were found to correlate with an increased symptom burden, including anxiety and depression, indicating that CGRP may serve as a prognostic factor for psychological outcomes following sSAH.
Article Synopsis
- Postoperative spinal epidural hematoma (pSEH) is a rare but serious complication occurring in 0.69% of patients after spinal decompression surgery, often leading to neurologic impairment if not treated promptly.
- A study of 6,024 patients identified anticoagulant use, abnormal preoperative coagulation tests, and smoking as significant risk factors for developing pSEH, with multiple-level surgeries also showing a trend toward increased risk.
- Patients presenting only with pain tend to have better recovery outcomes, whereas those with paraplegia face a higher likelihood of poor neurologic recovery.
Hydrocephalus with the need for shunt placement is a common sequela after aneurysmal subarachnoid hemorrhage (aSAH). In 2009 Chan et al. published a formula to predict shunt dependency in SAH patients, the failure risk index (FRI).
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