[Studies on the effect of cephradine, cefuroxime, lincomycin and amikacin on complement levels in experimental animals].

Rabbits were injected intramuscularily with antibiotics in mean therapeutic doses (calculated by body weight) for the period of 7 days. Group I received cephradine, group II--cefuroxime, group III--lincomycin and group IV--amikacin. Determination of complement level by CH50 method was performed before application of antibiotics and at 7, 14, 28 and 42 day of the study.

[Studies of the effect of cephradine and lincomycin on dynamics of selected parameters of nonspecific cellular immunity in experimental animals].

Rabbits of group I received cephradine i.m. and of group II lincomycin in mean therapeutic doses (calculated by body weight) for seven days.

[Investigations concerning the influence of cefuroxime and amikacin on dynamics of selected parameters of nonspecific cellular immunity in experimental animals].

Rabbits divided into two groups were injected intramuscularly antibiotics amikacin or cefuroxime in doses corresponding to mean therapeutic doses for seven days. Blood samples for determination of values of phagocytosis reaction (percentage of phagocytizing neutrophils, phagocyte index) and NBT test were taken before application of antibiotics and on 7, 14, 28 and 42 day of study. After application of cefuroxime significant decrease of NBT value was observed at the 14th day, whereas the percentage of phagocytizing neutrophils was changing at 7 and 14 day.

[Dynamics of the Paul Bunnel-Davidsohn test during infectious mononucleosis].

The study was aimed at establishment whether dependence exists between severity of clinical course of infectious mononucleosis and the level of heterophilic antibodies in the PBD test. Antibody titers were measured three times during illness in 34 persons with infectious mononucleosis, divided into two groups: I--patients with moderate course of the disease and II--patients with moderate-severe course. In five persons out of 34 tested negative PBD test result was obtained, although these patients exhibited symptoms on mononucleosis confirmed by other laboratory methods.

[Susceptibility to nitrofurantoin, biseptol and nalidixic acid of E. coli strains isolated from urine in the years 1983-1990].

The group of microorganisms causing urinary tract infections includes the Enterobacteriaceae family, particularly E. coli, being the most commonly detected etiologic factor of the above infections. Research was conducted from 1983 to 1990 on 1102 E.