Publications by authors named "A Szczepkowska"
Article Synopsis
- The study aimed to analyze differences in maternal vascular health and blood flow parameters among three groups of pregnant women: those with gestational diabetes mellitus (GDM), those with pre-existing diabetes mellitus (DM), and those without diabetes.
- It involved a large sample of 6,350 women to gather data on various cardiovascular measurements at 35-37 weeks of gestation, noting that a significant portion of women with GDM were treated with diet, metformin, or insulin.
- Findings revealed that women with GDM and pre-existing DM had higher cardiac output, heart rate, and blood pressure compared to those without diabetes, while treatment types within the GDM group mainly affected heart rate.
Maternal vascular indices at 36 weeks' gestation in pregnancy with small or growth-restricted fetus.
Ultrasound Obstet Gynecol
October 2024
Objective: To compare maternal vascular indices and hemodynamic parameters at 35-37 weeks' gestation in pregnancies complicated by delivery of a small-for-gestational-age (SGA) or growth-restricted (FGR) neonate.
Methods: This was a prospective observational study of women with a singleton pregnancy attending for a routine hospital visit at 35 + 0 to 36 + 6 weeks' gestation. The visit included recording of maternal demographic characteristics, medical history, vascular indices and hemodynamic parameters, which were obtained using a non-invasive operator-independent device and included pulse-wave velocity, augmentation index, cardiac output, stroke volume, central systolic and diastolic blood pressure, total peripheral resistance and heart rate.
Caffeine is one of the most widely consumed psychoactive drugs in the world. It easily crosses the blood-brain barrier, and caffeine-interacting adenosine and ryanodine receptors are distributed in various areas of the brain, including the hypothalamus and pituitary. Caffeine intake may have an impact on reproductive and immune function.
View Article and Find Full Text PDFMaternal cardiovascular function in midgestation is related to placental angiogenesis.
Ultrasound Obstet Gynecol
August 2024
Objective: To investigate whether angiogenic markers of placental function are associated with maternal cardiac function and hemodynamic responses at 19-23 weeks' gestation, controlling for maternal risk factors and pregnancy complications.
Methods: This was a prospective study of women with singleton pregnancy attending King's College Hospital, London, UK, for a routine hospital visit at 19-23 weeks' gestation. We recorded maternal characteristics and measured mean arterial pressure (MAP), maternal heart rate, serum placental growth factor (PlGF) and soluble fms-like tyrosine kinase-1 (sFlt-1).
Objectives: The Polish criteria for "intrauterine death" include fetal demise after 22 weeks of gestation, weighing > 500 g and body length at least 25 cm, when the gestational age is unknown. The rate of fetal death in Poland in 2015 is 3:10,000. In 2020, 1,231 stillbirths were registered.
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