Publications by authors named "A Sylla"
This paper investigates some properties of the large time behaviour of the solutions of a spatially distributed system of equations modelling the evolutionary epidemiology of a plant-pathogen system. The model takes into account the phenotypic trait and the mutation of the pathogen, which is described by a non-local operator. We roughly speaking prove that the solutions separate the phenotype trait from the spatio-temporal evolution in the large time asymptotic.
View Article and Find Full Text PDFBackground: To meet the WHO target of eradicating yaws by 2030, highly sensitive and specific diagnostic tools are needed. A multiplex Treponema pallidum-Haemophilus ducreyi loop-mediated isothermal amplification (TPHD-LAMP) test holds promise as a near-patient diagnostic tool for yaws and H ducreyi. We conducted a prospective evaluation in Cameroon, Côte d'Ivoire, Ghana, and the Republic of the Congo to determine the diagnostic accuracy of the TPHD-LAMP test, as well as to assess its acceptability, feasibility, and cost.
View Article and Find Full Text PDFArticle Synopsis
- Integrated approaches to mapping skin Neglected Tropical Diseases (NTDs) may optimize resource allocation, but extensive data covering multiple endemic countries was previously lacking.
- Between March 2021 and March 2023, integrated case searches were conducted in Cameroon, Côte d'Ivoire, and Ghana, screening over 61,000 individuals for various skin conditions including yaws and other NTDs.
- The findings revealed that 18.6% of those screened had skin lesions, with the majority being children; yaws was confirmed in a varying proportion of cases across the three countries, while scabies and fungal infections were the most commonly diagnosed conditions.
Article Synopsis
- Pathogens like bacteria, fungi, and viruses live in soil and water and can cause infections in humans and animals, especially from decaying matter.
- About one-third of diseases in humans are caused by these pathogens, which can survive outside living things for a long time.
- Researchers are studying how a specific pathogen called Mycobacterium ulcerans spreads in water and found that it's really important to understand how these germs live and grow to better prevent diseases caused by them.
Article Synopsis
- - Yaws, caused by the bacterium Treponema pallidum ssp. pertenue, is a major health issue in tropical West Africa and the South Pacific, particularly impacting children in areas lacking hygiene and sanitation.
- - A study in Ghana, Cameroon, and Côte d'Ivoire found diverse beliefs about yaws transmission among locals, with many attributing it to germs or contaminated water, while some linked it to witchcraft, and a low percentage recognized person-to-person contact as a method of transmission.
- - Most participants preferred seeking care from hospitals or healthcare professionals if diagnosed with yaws, but there was a significant reliance on traditional healers in Côte d'Ivoire, highlighting the necessity for increased community education and awareness