Publications by authors named "A Surbone"

Gynecological cancers quite often affect young women who wish to preserve their fertility. In addition, with the advancement in age of first pregnancies, this problem has currently taken on a significant scale. Most often, fertility preservation is possible provided that the cancerous tumor is discovered at an early stage and of a non-aggressive histological nature.

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Article Synopsis
  • A study was conducted to evaluate the effectiveness of the Womed Leaf, a degradable polymer film, for treating moderate to severe intrauterine adhesions (IUA) in women undergoing hysteroscopic surgery.
  • The PREG-2 trial was a multicenter, double-blind, randomized controlled trial, involving 160 women who were divided into two groups: one received the Womed Leaf after surgery while the other did not.
  • Results showed that the Womed Leaf significantly improved the reduction of IUAs compared to the control group, with a higher percentage of women showing no adhesions and no serious adverse events related to the device, confirming its safety and effectiveness.
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Over the past 40 years there has been a worldwide critical change in the field of assisted reproduction technology (ART), leading to the increased application of single blastocyst transfer, which is extremely important to avoid the risks of multiple pregnancy and associated complications for both mother and babies. Indeed, advancements in ART over the last few decades have been obtained thanks to several improvements, including ovarian stimulation, embryo culture conditions and, of course, progress in cryopreservation methods, especially with the application of vitrification. The ability to cryopreserve human embryos has improved significantly with vitrification compared to the initially adopted slow-freezing procedures.

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Objective: To describe a case of utero-ovarian transposition (UOT) before pelvic radiation in a patient with rectal cancer and provide a systematic literature review on all reported cases of UOT.

Methods: We performed a prospective collection and revision of clinical, intraoperative, and postoperative data from a patient who underwent UOT. In addition, a systematic review of the literature available to date on all cases of UOT was realized, and 14 patients from 10 articles were included.

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Recurrent miscarriages have a major psychological and somatic impact, as well as a significant economic burden. An etiological work-up should be offered after two or three miscarriages, the threshold varying from one scientific society to another. However, the proposed biological work-up must be justified by scientific evidence.

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