The Role of vIL-6 in KSHV-Mediated Immune Evasion and Tumorigenesis.

Kaposi's sarcoma-associated herpesvirus (KSHV) is a double-stranded DNA gamma herpesvirus. Like other herpesviruses, KSHV establishes a latent infection with limited gene expression, while KSHV occasionally undergoes the lytic replication phase, which produces KSHV progenies and infects neighboring cells. KSHV genome encodes 80+ open reading frames.

Design and Test of a Calibration System for Avalanche Photodiodes Used in X-Ray Compton Polarimeters for Space.

The development and calibration of a measurement system designed for assessing the performance of the avalanche photodiodes (APDs) used in the Compton scattering polarimeter of the CUSP project is discussed in this work. The designed system is able to characterize the APD gain GAPD and energy resolution across a wide range of temperatures (from -20 °C to +60 °C) and bias voltages Vbias (from 260 V to 410 V). The primary goal was to experimentally determine the GAPD dependence on the and Vbias in order to establish a strategy for stabilizing GAPD by compensating for fluctuations, acting on Vbias.

Synthetic Imaging Radar Data Generation in Various Clutter Environments Using Novel UWB Log-Periodic Antenna.

In short-range microwave imaging, the collection of data in real environments for the purpose of developing techniques for target detection is very cumbersome. Simultaneously, to develop effective and efficient AI/ML-based techniques for target detection, a sufficiently large dataset is required. Therefore, to complement labor-intensive and tedious experimental data collected in a real cluttered environment, synthetic data generation via cost-efficient electromagnetic wave propagation simulations is explored in this article.

Strategic Switching from Conventional Urea to Nano-Urea for Sustaining the Rice-Wheat Cropping System.

In the face of declining crop yields, inefficient fertilizer usage, nutrient depletion, and limited water availability, the efficiency of conventional NPK fertilizers is a critical issue in India. The hypothesis of this study posits that nano-nitrogen could enhance growth and photosynthetic efficiency in crop plants compared to conventional fertilizers. For this, a randomized block design (RBD) field experiment was conducted with six treatments: no nitrogen (T1), 100% N through urea (T2), and varying levels of N replacement with nano-nitrogen (33%: T3; 50%: T4; 66%: T5; and 100%: T6).

Differential Transcriptional Landscape of Vero Cells During Dengue Virus 2 Infection in the Presence of Sinococuline.

Dengue virus (DENV) is transmitted by genus mosquitoes and is responsible for dengue fever (DF) and other severe diseases, posing a significant challenge to the global health system. Currently, anti-dengue pharmacological treatment options are not available. Earlier, we demonstrated that Sinococuline has potent anti-dengue activity and prevents virus infection.