Publications by authors named "A Sumiyoshi"

Article Synopsis
  • Copy number variants (CNVs) are linked to psychiatric disorders and brain structure changes, but the specific gene effects within the CNV regions, like 22q11.2, are still unclear.
  • This study focuses on Tbx1, a gene in the 22q11.2 region, exploring how it influences brain volume and behaviors through a detailed analysis of Tbx1 heterozygous mice using magnetic resonance imaging.
  • Results showed decreased volumes in key brain areas associated with social behavior and learning, while some auditory regions were larger, highlighting the nuanced impacts of Tbx1 on brain structure and function.
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Background: The tip-detection method and the retrograde approach have been acknowledged as a second-line strategies for chronic total occlusion (CTO) percutaneous coronary intervention (PCI) when conventional antegrade wiring strategies are ineffective. The aim of this study is to compare the efficacy between both strategies for complex CTO PCI.

Methods: We retrospectively enrolled 170 consecutive CTO PCI cases and separated them into 295 adopted strategies.

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Article Synopsis
  • - The study aimed to compare the safety and effectiveness of transluminal foam sclerotherapy combined with endovenous laser ablation (EVLA) against EVLA alone for treating small saphenous vein incompetence, focusing on changes in the venous clinical severity score (VCSS) over one year.
  • - Researchers conducted the study by using a sheath for foam sclerotherapy during the EVLA procedure, assessing various outcomes such as VCSS changes, reflux recurrence, and complications at multiple time points after treatment.
  • - Results indicated that while the change in VCSS wasn't significantly impactful, the combination treatment (TLFS + EVLA) led to lower rates of residual or recurrent reflux compared to EVLA alone, suggesting TLFS
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We develop and evaluate an artificial intelligence (AI)-based algorithm that uses pre-rotation atherectomy (RA) intravascular ultrasound (IVUS) images to automatically predict regions debulked by RA. A total of 2106 IVUS cross-sections from 60 patients with de novo severely calcified coronary lesions who underwent IVUS-guided RA were consecutively collected. The 2 identical IVUS images of pre- and post-RA were merged, and the orientations of the debulked segments identified in the merged images were marked on the outer circle of each IVUS image.

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Article Synopsis
  • The study introduced a new method called tip detection (TD) combined with a special wire (CP12ST) to enhance the effectiveness of treating chronic total occlusion (CTO) in coronary procedures.
  • Researchers compared the success rates and procedural times of the TD method with an existing technique (Stingray) using a different wire (CP20) in 54 total cases.
  • The findings showed that the TD method led to a significantly higher success rate (100% vs 67%) and shorter procedural times (145 minutes vs 185 minutes), with few complications in both groups.
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