Publications by authors named "A Suchak"

Article Synopsis
  • Maxillary osteotomy is a surgical procedure performed to correct facial growth issues in patients with cleft lip and palate, but it can lead to velopharyngeal insufficiency, causing hypernasality in speech.* -
  • The study examined 20 patients through various speech assessments before and after surgery to identify factors predicting the development of hypernasality.* -
  • Significant predictors of hypernasality post-surgery were found to be the closure ratio and the amount of palate contacting the posterior pharyngeal wall, highlighting key areas for monitoring in recovery.*
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Article Synopsis
  • The study aimed to evaluate how maxillary osteotomy impacts velopharyngeal function in patients with cleft lip and palate (CLP) through various instrumental measures.
  • At three time points (pre-surgery, 3 months post-surgery, and 12 months post-surgery), nasalance and velar parameters were assessed using specific tools and methods.
  • Results indicated a significant adverse effect on nasalance after maxillary osteotomy and suggested the need for earlier post-surgical evaluations, highlighting that changes in velopharyngeal function appear to be permanent.
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Melanotic neuroectodermal tumours of infancy (MNTI) are particularly rare and although predominantly benign, are infiltrative and locally aggressive. Presenting in the first year of life, prompt diagnosis and effective management are critical in minimizing morbidity and the risk of recurrence. A retrospective review of 11 MNTI managed at Great Ormond Street Hospital (GOSH) from 2000 to 2017 was undertaken.

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A deproteinized natural cancellous bone mineral (B) was studied in a cell culture model for its anabolic potential using two radiolabelled steroid substrates, 14C-testosterone (14C-T) and 14C-4-androstenedione (14C-4-A) independently; in the presence or absence of the anti-androgen finasteride (F) and minocycline (M). Culture medium was assayed for the biologically active metabolite 5 alpha-dihydrotestosterone (DHT) a marker of regenerative potential and wound healing. Confluent monolayer cultures of human periosteal fibroblasts were incubated in Eagle's minimum essential medium with each of the substrates 14C-T and 14C-4-A.

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We describe the case of a male patient who presented with anisocoria, and was initially diagnosed with an acute Adie's tonic pupil. On subsequent laboratory testing, he was found to have neurosyphilis. Magnetic resonance imaging demonstrated enhancement of the right oculomotor nerve.

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