Publications by authors named "A Subbiah Pandi"
Transformer (TRA2B) is a serine/arginine-rich (SR)-like protein family that regulates the alternative splicing of several genes in a concentration-dependent manner. Amplification of the TRA2B gene, which codes for TRA2B, occurs in several malignancies, including those of the lung, cervix, head and neck, ovary, stomach, and uterine.
View Article and Find Full Text PDFObjective: This study aimed to investigate the role of a novel m6A and cell cycle regulator YWHAG in oral squamous cell carcinoma (OSCC) by analyzing its expression and functional implications.
Design: Tumor samples (n = 51) and adjacent non-tumor samples (n = 38) were collected from patients with OSCC, and cell lines were processed. YWHAG mRNA expression was assessed using quantitative reverse transcription PCR (RT-qPCR) analysis.
Background Triggering receptor expression on myeloid cells-1 (TREM1) belongs to the immunoglobulin superfamily and is implicated in various conditions, including infectious and non-infectious diseases, autoimmune disorders, and cancer. Notably, TREM1 is significantly dysregulated in numerous cancer types. However, the underlying mechanism driving TREM1 mRNA expression in cancers remains unclear.
View Article and Find Full Text PDFArticle Synopsis
- - The study explores the morphology of two thrip species, *Thrips tabaci* and *Thrips parvispinus*, using advanced imaging techniques like optical microscopy and field emission scanning electron microscopy (FE-SEM), alongside molecular methods for identification.
- - Key morphological differences were noted, including variations in antennae structure, ocelli color, forewing setae, and abdominal features, which help differentiate the two species.
- - Molecular analysis confirmed the identities of the two thrips species with a high similarity to existing genetic data, highlighting the importance of combining morphological and molecular techniques for thorough species identification.
Background: Emerging research has identified the N6-methyladenosine (m6A) modification and its regulatory enzymes, including methyltransferase 5 (METTL5), as critical players in cancer biology. However, the role of METTL5 in oral squamous cell carcinoma (OSCC) remains poorly understood.
Materials And Methods: We conducted a comprehensive study to investigate the expression and implications of METTL5 in OSCC.