Associations between the thyroid panel and serum protein concentrations across pregnancy.

Establishing any characteristic associations between the serum parameters of thyroid function and serum proteins in pregnancy may aid in elucidating the role of the thyroid gland in the regulation of pregnancy-specific metabolic processes and in selecting candidate biomarkers for use in their clinical assessment. Concentrations of thyroid stimulating hormone (TSH), free tri-iodothyronine (fT3) and free thyroxine (fT4), six electrophoretically separated protein fractions (albumin, alpha-1-, alpha2-, beta-1-, beta-2- and gamma-globulins), representative proteins-albumin (ALB), transferrin (TRF), alpha-2-macroglobulin (AMG) and ceruloplasmin (CER) were measured in 136 serum samples from 65 women in their consecutive trimesters of pregnancy. The concentrations of TSH, fT4 and fT3 were significantly correlated (p < 0.

Arctic Ice Loss Threatens National Security: A Path Forward.

Global warming is causing a dramatic reduction in Arctic sea and land ice and thawing permafrost. Because of the Arctic's role in influencing climate, loss of Arctic ice is affecting weather patterns globally and in the Northern Hemisphere in particular. Events such as droughts and coastal flooding, exacerbated by global warming, result in food and water shortages and mass human migrations that can destabilize governments and threaten U.

Can variability of serum electrophoretic fractions during pregnancy provide knowledge about maternal and fetal health.

Aim: Characteristics of variability of concentrations total protein and its electrophoretic fractions in serum of healthy pregnant women between successive trimesters and post-partum for initial classification of proteins involved in specific metabolic processes associated with pregnancy.

Methods: Total serum protein concentrations were measured by biuret method and serum protein fractions were electrophoretically separated in 166 serum samples collected from healthy pregnant women in three trimesters of pregnancy (1st, n = 55; 2nd, n = 42; 3rd, n = 39) and in post-partum (n = 30), and in 20 samples from nonpregnant controls.

Results: Across pregnancy, there were gradual, but occurring at different rates, decreases over time in serum total protein, albumin and gamma globulins compared to controls (P < 0.

The association between clinical and laboratory parameters in thyroid disease and nonthyroidal illness in young women.

Objective: Evidence from epidemiological and clinical studies strongly suggest that young women in the preconception period are a group at risk for thyroid disorders which may lead to further aggravation of pre-existing chronic thyroid disease and complications during pregnancy.

Materials And Methods: This paper is a literature review focusing on articles published in English between 2014-2017 searched in Medline database using terms 'young women', 'subclinical hyperthyroidism', 'subclinical hypothyroidism', 'nonthyroidal illness syndrome', 'obesity', 'depression'.

Conclusions: Clinical assessment of young female patient including that of obtaining full medical history with a focus on the perceived changes in appearance, psychological symptoms and menstrual irregularities supported by laboratory tests indicative of metabolic status and characteristic changes in thyroid functions, may be the key to well-reasoned and justified individual therapeutic decisions.

Enhancing the Applicability of Satellite Remote Sensing for PM2.5 Estimation Using MODIS Deep Blue AOD and Land Use Regression in California, United States.

We estimated daily ground-level PM2.5 concentrations combining Collection 6 deep blue (DB) Moderate Resolution Imaging Spectroradiometer (MODIS) aerosol optical depth (AOD) data (10 km resolution) with land use regression in California, United States, for the period 2006-2012. The Collection 6 DB method for AOD provided more reliable data retrievals over California's bright surface areas than previous data sets.